Immunocorrecting effect of combined use of magnetolaser therapy and red light in the complex treatment of patients with chronic nonbacterial prostatitis

Kulishova T.V., Neymark A.I., Kryanga A.A., Gazamatov A.V.

Aim. To evaluate the immunocorrecting effect of complex treatment of patients with chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) with the use of combined exposure to magnetolaser therapy (MLT) and red light.

Materials and methods. The study included 120 men with a diagnosis of CP/CPPS (III B), in the acute stage. All patients were randomized into 2 groups. The main group consisted of 60 patients who received a basic treatment, including drug therapy, prostate massage, diet therapy, therapeutic exercises, as well as combined effects of MLT and red light. The comparison group consisted of 60 patients receiving only basic treatment. The immunocorrecting effect of the treatment was evaluated in the dynamics before and immediately after therapy by measuring the concentration of secretory immunoglobulin A (sIgA) in the prostate secretion, as well as tumor necrosis factor alpha (TNFα) and interleukin-1 beta (IL-1β).

Results and discussion. In the main group of studied after treatment there was an increase in the concentration of sIgA in the secretion of prostate by 2,1 times (р<0,001), a decrease in the concentration of TNF-α by 1,5 times (р<0,001) and IL-1β by 1,9 times (р<0,001), which indicates a pronounced immunocorrecting effect of the therapy. In the comparison group, the immunocorrecting effect of the basic treatment was less pronounced. Comparative analysis of the results of the study between the main group and the comparison group showed the presence of statistically significant differences in all indicators of local humoral factors of the immune system immediately after treatment.

Conclusion. The method treatment of patients with CP/CPPS using combined use of MLT and red light has a great immunocorrecting effect in comparison with the basic treatment.

Authors declare lack of the possible conflicts of interests

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chronic prostatitis/chronic pelvic pain syndrome, complex therapy, cytokines, combination physiotherapy

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