Prevalence of lower urinary tractsymptoms in men according to the results of population research

Apolihin O.I., Sivkov A.V., Zolotuhin O.V., Shaderkin I.A., Voytko D.A., Prosyannikov M.Yu., Ivanov V.M., Golovanov S.A., Katibov M.I.

Introduction. In Russia, until now, methodologically correctly organized population studies of LUTS have not been conducted. In this regard, from 2013 to 2016. Research Institute of Urology and Interventional Radiology. N.A Lopatkin conducted a population-based study of the prevalence of LUTS in men in the Bobrovsky district of the Voronezh region, with an assessment of the depenence of symptoms on age and a number of other anthropometric indicators.

Materials and methods. The study population is 40-69 years old men, divided into age groups: 40-49; 50-59; 60-69. Methods of research: questionnaire using the IPSS questionnaire, meas-urement of height (cm), waist circumference (cm), weight (kg), body massindex calculation – BMI(kg/m2). Statistical processing of datawith the definition of the relationship of LUTS with age and anthropometric indicators.

Results. 4876 men were examined, the average age was 54.7 + 0.1. The mean score of IPSS in the general population is 2.8 ± 0.1 points, and in the group with LUTS (IPSS> 1) – 4.7 ± 0.1. Distribution of respondents, depending on the severity of LUTS: IPSS 1-7 (n = 2306) – 47.3%; IPSS 8-19 (n = 496) – 10.2%; IPSS> 19 (n = 39) – 0.8%. The average score of IPSS in the groups was: 2.4 + 0.1; 13.8 + 0.1 and 24.5 + 0.5,respectively.The proportion ofrespondentsin the general populationwith IPSS> 8was 11.0%, 18.8% among all patientswith LUTS. The number of menwith IPSS> 8 points by age groupwas distributed as follows: 40-49 years – 4.9%; 50-59 years – 9.4%; 60-69 years old – 18.8%.The most frequent of all the symptomswas nocturia, itwasrevealed in 52.0% (n = 2535), which accounted for 29.7% of all LUTS. The share of othersymptomswas modest: from 9.2 to 15.0%.Anthropometric indicators: height 174.3 ± 0.1 cm; bodyweight 83.5 ± 0.2 kg; BMI 27.5 ± 0.1;waist cir-cumference 93.2 ± 0.2 cm. Statistical analysis confirmed a directrelationship between the severity of LUTS and age: p 1were older, had significant(p 8 and IPSS> 20 did notreveal significant differences (p> 0.05), except for age indices (p 8.Correlation analysisin the general population did not reveal a relationship between the sum of IPSS respondents' scores and their rostom, body weight, BMI, waist circumference.

Conclusion. The prevalence of LUTS in men 40-69 years in the study region was> 1 – 58.2% for IPSS>, and for IPSS> 8 – 11.0%. The incidence of moderate and severe LUTS (IPSS> 8) progres-sively increased with age: from 15.3 to 26.2%. The relationship between the total sum of IPSS scores and the weight-for-weight indicators of respondentswas not confirmed, norwasthe dependence on them of the symptoms of the phases of accumulation and emptying.

Authors declare lack of the possible conflicts of interests.

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lower urinary tract symptoms (LUTS), population study, prevalence, correlation with height and weight indices, correlation with severity of symptoms of accumulation and emptying phases, forecasting the number of men with LUTS

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