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G.D. Efremov - articles list
Выпуск №1 за 2020 год
Introduction. Bladdercancer (BC) represents one of the most frequent disease in the structure of morbidity and mortality among malignant neoplasms in human. At the moment, there is a large amount of...
Выпуск №3 за 2019 год
Contacts: Kirpatovskiy Vladimir Igorevich, vladkirp@yandex.ru
Introduction. Regenerative medicine is an actively developing area of experimental research. ?e protective effect of low-differentiated...
Выпуск №2 за 2016 год
Relevance. PCA3 demonstrated a high diagnostic value in relation to prostate cancer. The few studies of clinical and cost-effectiveness of PCA3 dedicated to costly test "Progensa". Economic...
Выпуск №4 за 2015 год
More than 13 thousand cases of
bladder cancer are registered in
Russia annually that represents an actual
problem in modern urologic oncology.
Searching and characterization of
new molecular markers...
Выпуск №3 за 2015 год
Neuroendocrine differentiation (NED) of the prostate cancer (PCa) is a carcinoma of prostate containing neuroendocrine (NE) component. According to evidence, NED is present in approximately 40% of...
Выпуск №2 за 2015 год
Over the past 20 years a large number of prostate cancer (PCa) markers have been proposed. A combination of PCA3 and TMPRSS2-ERG is among them. The real-time RT-PCRbased method for РСА3 and TMPRSS2-...
Выпуск №3 за 2014 год
More than 20-years experience of PSA
use for PCa screening has lead to a life
expectancy growth and reduction of
mortality in PCa patients. On the other
side, widespread use of PSA resulted in
some...
Выпуск №2 за 2014 год
The pathogenetic importance of chronic ischemia of the pelvic organs in the development of benign prostate hyperplasia (BPH) and concurrent bladder dysfunction was investigated in chronic experiments...
Выпуск №1 за 2014 год
The most informative immunological
analysis to reveal neuroendocrine
differentiation (NED) in prostate
cancer diagnostics is evaluation of
Chromogranin A (ChA) level. Rhe
value of ChA in the...
Выпуск №4 за 2013 год
In experiment on 15 male rats of different age
it was shown, that old rats in the age of 2 years
have definitive age-related changes in the
prostate, analogous to the benign prostatic
hyperplasia...
Выпуск №3 за 2013 год
The studies of the last years showed, that
prostate specific antigen (PSA) is not
absolutely organ specific and could be
detected in endometrium, in mammary
gland, in breast milk, in adrenal tumors,...
Выпуск №3 за 2013 год
Castration-refractory prostate cancer (CRPC)
makes up 5-20% of all prostate cancer (PCa)
cases. Basically the reason for CRPC is a
regulation breakdown of the androgen
receptors (AR). The altered ARs...
Выпуск №3 за 2013 год
Renal cancer is a heterogeneous group of
tumors, the most common of which is the
clear cell carcinoma, less common papillary
and chromophobe carcinomas. Pathological
examination faces difficulties...
Выпуск №4 за 2011 год
One of the biggest problems in the diagnosis
of prostate cancer (PCa), which
distinguishes it from many other solid
tumors, is the difficulty of visualization
of the tumor process by using modern...
Выпуск №2 за 2013 год
The inhibitors of the phosphodiesterase
type 5 (iPDE-5) are today the first line
agents for the therapy of the erectile
dysfunction (ED). The data regarding
their effect on the male fertility is...
Выпуск №3 за 2012 год
Ultrastructural studies have shown a wide morphological diversity of neuroendocrine cells (NEC), which is correlated with a large number of known secreted into the blood substances, including...
Выпуск №1 за 2011 год
Brief definition of immunohistochemical assay was given in this article. The role of immunohistochemical assay in prostate cancer diagnostics was shown. Immunohistochemical markers were...
