Яровой С.К.

A retrospective analysis of antiulcer prophylaxis efficacy, based on the results of 8346 surgical interventions on the organs of the urogenital systemand 1960 esophagogastroduodenoscopies. A comparative analysis of the efficacy of application of H2 – receptor blockers of II and III generation proton pump blockers in anti-ulcer prophylaxis. With small volume urological surgeries antiulcer prophylaxis should be done only to patients with concomitant gastric ulcer and duodenal ulcer.

Medications that inhibit adrenergic receptors, are used in clinical practice for a quite long time - since 1918. Discovery of different subtypes of α-adrenergic receptors and the clarification of their role allowed to create selective α1-blockers, which, compared with non-selective α-blockers have far less side effects on the cardiovascular system.

Analysis of main positions of the antibacterial prophylaxis methods before surgical interventions and main requirements for antibacterial prophylaxis medications. Approaches to empirical antibiotic prophylaxis in surgeries on kidneys, ureters, bladder, prostate, scrotum organs, as well as reconstructive interventions using a fragment of intestine are stated.

Urolithiasis takes one of the first plac¬es in the structure of urological diseas¬es. Kidney and urinary tract stones are detected in 30-45% of patients admit¬ted to urological hospitals.

The article reports results of sensitivity analysis to a new antibiotic tigecycline (group of glycyl-cyclines) of 1210 strains of the most common causative agents of infectious and inflammatory diseases of the genitourinary system. Biomaterial was taken from patients suffering from recurrent infectious and inflammatory diseases of the genitourinary system: secondary chronic pyelonephritis with a background of urolithiasis, neurogenic bladder dysfunction, abnormalities of the urogenital tract (965 pers. – 79.6%), chronic prostatitis (154 pers.

The paper analyzes the statistics of Moscow City Clinical Hospital № 47, in providing urological care for 352 HIV-infected patients during the period June 1996 to May 2011.

At present time usage of radiopaque contrast agents (RCA) is indispensable part of diagnostic search in urological and oncourological patients. During it's evolution RCA's physicochemical features and terms of production improved. RCA for urographic and angiographic investigations must answer the requirements of optimal physicochemical features and biological characteristics: low plasma proteinbinding, high filtration rate, good tolerance. Visualization quality depends on the amount of injected RCA and the number of iodine atoms in the contrast agent molecule.

In the paper we present a result of study of antibiotics (vancomycin, cefotaxime, amicacin, meropenem, ciprofloxacin) effect on cytokine production by mononuclear fraction of periferal blood cells in normal condition and in chronic renal failure.

In the paper results of examination and treatment of 27 patients suff ering from recurrent phosphate nephrolithiasis which were treated at the Research Institute of Urology were analyzed. Patients with chronic renal failure grade II-III and hyperparathyroidism were excluded. Along with overall assessment of renal function (glomerular fi ltration rate, daily protein excretion, inorganic phosphate excretion etc.) and spectral analysis of excreted calculi, all patients underwent assessment for bone mineral density of calcaneal tuber by osteodensitometry using Calscan device (Lund, Sweden).