Кирпатовский В.И.

In narcotized dogs, electrical impedances of prostate and urinary bladder were recorded simultaneously with vesical pressure to assess neural control and circulation in these organs in vivo with the method of bioimpedance harmonic analysis. Regional sympathetic and parasympathetic activities were assessed by the magnitude of Mayer (M) and respiratory (R) peaks, correspondingly. Circulation in these organs was evaluated according to the magnitude of the first pulsatile (cardiac) harmonic C1.

This article is devoted to the description of the method of extracorporeal indirect electrochemical oxidation (EIEBO) in patients with infectious inflammatory complications and grade I endotoxicosis. The distinguishing feature of the EIEBO from the adopted intracorporeal method of oxidation is that blood is being processed using 0.06% solution of the sodium hypochlorite (SH) within the venous extracorporeal line, created using special equipment.

In experiment on 15 male rats of different age it was shown, that old rats in the age of 2 years have definitive age-related changes in the prostate, analogous to the benign prostatic hyperplasia (BPH), in a form of increase in the prostatic mass and typical histological picture.

This article is devoted to the prognostic method, which can show, whether if the urological infection will have a lethal or favorable outcome.

The scientific data of the last years shows that increased level of the testosterone in the blood is not a main factor of the development of benign prostatic hyperplasia (BPH), though the exogenous supply in big doses is used for the induction of BPH in the experimental animals. Moreover the growth of the frequency of the BPH is linked to the low level of the testosterone, which is a part of the ageing and a consequence of the pathological conditions, such as metabolic syndrome or diabetes.

The inhibitors of the phosphodiesterase type 5 (iPDE-5) are today the first line agents for the therapy of the erectile dysfunction (ED). The data regarding their effect on the male fertility is controversial.

In this study we have investigated the influence of sodium hypochlorite (SH) on the blood leukocytes in rats (experimental part) and the possible applications of SH in patients with acute pyelonephritis. Experimental part was performed on 35 white inbreed male rats. Clinical part included 2 groups of patients from urological clinic.

The experiments were made using 20 mature male rats (line “August”) with a mass of 280-320 g. In 10 rats metabolic changes typical for metabolic syndrome (MS) were induced using high-calorie diet (adding of 20% margarine to standard diet and 20% of fructose to the water during 3 months), bilateral orchiectomy (to create androgen deficiency) and stress (immobilization stress during 1 day in the end of the observation period).

In chronic experiments with 30 male white inbreed rats we have investigated the influence of high-calorie diet (addition of 20% margarine to the formula feed and 20% fructose to the water), androgen deficiency (bilateral orchiectomy) and stress (due to immobilisation) and their combination on the biochemical markers of kidneys and liver function.

The paper is dedicated to the mechanism of adaptogenic effect of sodium hypochlorite (SH). The studies were performed in three groups of 45 albino male rats. Group of intact animals were 5 rats. The rats in the control group (n = 20) were daily intraperitoneally (i / p) administered for 1.5 ml of saline for 4 days. The rats in the experimental group (n = 20) were similarly injected with 1.5 ml 0.06% solution of SH. The results in the group of intact rats were considered the normal values.