Казаченко А.В.

In chronic experiments with 30 male white inbreed rats we have investigated the influence of high-calorie diet (addition of 20% margarine to the formula feed and 20% fructose to the water), androgen deficiency (bilateral orchiectomy) and stress (due to immobilisation) and their combination on the biochemical markers of kidneys and liver function.

Chronic pyelonephritis is one of the most common diseases complicating numerous urologic pathologies or occurring as an independent pathology. Chronic pyelonephritis due to insufficient and often non-effective management might cause renal failure, even after risk factors removal. New approaches in chronic pyelonephritis management required. According to publications bone-marrow mesenchymal stem cells can improve chronic inflammation because of cytokine complexes secretion.

Medical education is one the most important factors of providing high professional level of healthcare specialists. The basement of medical professional formation is postgraduate education, which at present day for a number of reasons do not manage the task of training of high qualified medical professionals. Existing postgraduate educational system in Russia wasn't reformed for more than 40 years!

In rat model perspective of two novel trends of preventing and treatment of acute post-ischemic renal failure (ARF) was investigated, in particular application of two drugs referred to novel class of antioxidants, which are selectively accumulated in mitochondria of renal tubular epithelium, which conditionally denoted as SkQ1 and SkQR, as well as administration of cultured human bone marrow-derived mesenchymal stem cells (BM-MSC) and cultured fetal renal cells (CRC).