ANDROLOGY

Introduction. According to Rosstat, the population of the Russian Federation as of January 2025 was 146.15 million, which is incredibly low for a country with a territory of 17.1 million square kilometers. According to official statistics for 2024, the country's population decreased by 599.000, and the negative trend of population decline continues, even at an accelerating rate. Therefore, the issue of reproductive security is becoming one of the most pressing issues in the country today.

Introduction. Erectile dysfunction (ED) occurs in more than half of men over 40 years of age, occupying a leading place in the sexual disorders structure. Herbal remedies can be used for initial treatment of ED. ED and testosterone deficiency syndrome are closely interrelated and when correcting these conditions, the specific treatment of both should be taken into account.

Aim: to evaluate serum total testosterone level changes in patients with ED during routine use of EFFEX® Tribulus (Evalar, Russia).

Introduction. In patients undergoing transurethral resection of the prostate for benign prostatic hyperplasia, lower urinary tract symptoms associated with overactive bladder often persist in the postoperative period. The search for effective conservative treatment regimens for this category of patients remains a relevant clinical issue.

Introduction. Endoscopic video surgery is a standard for large-volume benign prostatic hyperplasia (BPH). Various approaches exist: multiport, single-port, and robot-assisted; however, their comparative analysis remains relevant.

Aim: to comprehensively compare intra- and postoperative outcomes, functional results, pain syndrome, and cosmetic effects of single-port, multiport, and robot-assisted adenomectomy.

Introduction. The alfuzosin and solifenacin combination has previously demonstrated high efficacy and safety in patients with BPH and overactive bladder (OAB), including with severe LUTS, if cases of mechanical type of bladder outlet obstruction (BOO) were excluded. The present study aim was to confirm the efficacy and safety of such combination therapy in patients with severe urinary disorders according to uroflowmetry (UFM).

Introduction. Chronic prostatitis (CP) and chronic pelvic pain syndrome (CPPS) are the most prevalent urological disorders, affecting up to 14% of men and significantly reducing quality of life. The limited effectiveness of conventional treatment regimens increases interest in physiotherapeutic approaches, including extracorporeal shock wave therapy (ESWT), and in the use of enzymatic preparations.

Introduction. Currently, there has been an increase in the number of people suffering from infertility, while 20-50% of childless couples have problems associated with reproductive disorders in men. In Russia for the period 2000-2018. there was an increase in the number of men with infertility by 2.1 times. Male fertility is largely determined by the process of spermatogenesis. The importance of oxidative stress in the etiology of sperm dysfunction is now generally accepted and unquestioned.

Introduction. Postorgasmic illness syndrome (POIS) is a pathological condition that occurs after ejaculation and is manifested mainly by flulike symptoms. The exact prevalence and incidence of the syndrome are unknown. The National Institute of Health (NIH) of the United States classifies this syndrome as a genetic and rare disease. Few episodes of post-orgasmic malaise have been described in the literature, and they are mainly represented by clinical cases.

Introduction. The problem of male infertility remains a pressing issue in the field of reproductive medicine, as male infertility progresses year after year. The male reproductive microbiome is a complex community of microorganisms that inhabit various parts of the male body, including the urethra, prostate, and seminal vesicles. Research shows that the microbiome plays an important role in maintaining reproductive health and may influence fertility.

Introduction. Besides directly contributing to the pathogenesis of lower urinary tract symptoms, bladder outlet obstruction due to benign prostatic hyperplasia may lead to lower urinary tract dysfunction such as detrusor overactivity and decreased bladder contractility.