ANDROLOGY

Introduction. Premature (early) ejaculation is a common male sexual problem. Despite a significant number of proposed methods, there is still no consensus among doctors about the most effective methods of conservative and surgical treatment of this pathology.

Introduction. In this literature review we discuss the etiology, risk factors, and features of erectile dysfunction management in men with liver disease and cirrhosis.

Introduction. The relationship between chronic abacterial prostatitis/chronic pelvic pain syndrome (CP/CPPS) and male infertility is the subject of numerous studies, and therefore various methods for correcting pathospermia have been proposed. The main concept is that in one way or another it is necessary to create conditions for a more perfect penetration of drugs into the zone of the prostate-vesicular complex. In this regard, the search for new and pathogenetically substantiated methods of therapy for such a patient seems to be very relevant

Introduction. The problem of the pandemic caused by the COVID-19 virus is extremely relevant. It has been proven that SARS-CoV-2, which causes respiratory distress syndrome, is not only aggressive towards lung tissue, as was originally assumed. A promising direction in the study of the pathogenic properties of the pathogen is the effect on the male reproductive system.

Introduction. Early ejaculation mixed with ED is quite an often combination, mentioned in clinical guidelines. Management of these two conditions results in prescribing both SSRIs and PDE5i. But there is a lack of information about efficacy and safety of such combination.

Aims. The study objective is to evaluate effectiveness and safety of dapoxetine (NAO «Severnaya zvezda») 30/60 mg on demand combined with tadalafil (NAO «Severnaya zvezda») 5 mg OD for managing early ejaculation and erectile disfunction.

Introduction. Currently, there are conflicting reports in the literature about the impact of COVID-19 on male and female reproductive health, as well as the impact of hormonal status on the course of the disease. The basis for such concern is the high density of ACE2 receptors involved in the pathogenesis of COVID-19 on the surface of cells of the reproductive organs.

Purpose. To evaluate the effect of sex hormone levels on the course of COVID-19 in men and women, as well as the effect of COVID-19 on spermatogenesis.

Introduction. Damage of the sperm genetic material is one of the causes of male infertility, miscarriage and adverse ART outcomes. Treatment of patients with an increased level of sperm DNA fragmentation is a difficult task due to extremely limited number of treatment options. In this survey, we analyzed the available data on treatments of infertility associated with a high level of sperm DNA fragmentation.

Introduction. Benign prostatic hyperplasia (BPH) is one of the most common diseases among elderly and senile men. Currently the effective LUTS severity decrease due to the widespread alpha-blockers usage leads to the increasing numbers of patients with large (more than 80 cm³) and giant (more than 150 cm³) prostates glands at the moment of surgery. This forces urologists to search the optimal surgery methods to treat those patients.

Introduction. Chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) in men remains an unresolved problem of urology due in sufficienty stadied etiopathogenesis, methodological problems of diagnosis and, as a consequence, unsatisfactory results of treatment, which includes pharmacotherapy and non-drug interventions of various levels of evidence of their effectiveness, which mainly to alleviate the symptoms of the disease.

Introduction. One of the actual problems of modern urology and andrology is the study of the diagnostic significance of cystic formations of the epididymis. However, there are singal indications in the literature on the study of the composition of the contents of the cysts of the epididymis, and at the same time, due attention was not paid to the assessment of the inflammatory factor. Purpose of the work: determination of tumor necrosis factor alpha, interleukin-6 and interleukin-4 in the contents of the cysts of the epididymis.