Simulation of spermatogenesis disorders with chemotherapeutic agents – Ñisplatin and Doxorubicin
Introduction. Cisplatin and Doxorubicin have pronounced toxic effects on spermatogenesis. Modeling of spermatogenesis disorders using these drugs can become convenient and relevant when conducting preclinical studies to assess the specific activity of new drugs for the treatment of toxic cases of male infertility.
Objective. Тo evaluate the possibility of using Cisplatin and Doxorubicin for spermatogenesis disorders in vivo experiments.