ONCOUROLOGY

Introduction. Metastatic renal cell carcinoma (RCC) is the most difficult urological neoplasm form to treat. The last two decades have witnessed significant progress in the RCC treatment. A better understanding of oncogenesis has led to the development of several targeted therapies, including tyrosine kinase inhibitors (TKIs), vascular endothelial growth factor (VEGF) targeting agents, and mammalian target of rapamycin (mTOR) inhibitors.

Introduction. The three-dimensional (3D) imaging during laparoscopic procedures can improve the quality of that surgeries. There is a shortage of publications about the potential benefits of 3D navigation in laparoscopic surgery with urological diseases. Radical prostatectomy (RPE) is known as the gold standard of treatment of localized prostate cancer (PC), and investigation of imaging technologies in laparoscopic surgery in PC patients is a hot topic.

Introduction. Venous invasion and tumor thrombus formation are rare, but life-threatening complications of renal cell carcinoma (RCC), especially in combination with metastases, are considered significant adverse prognostic factors.

Aim. To systematize the existing knowledge and summarize the clinical experience of surgical treatment (open and robot-assisted surgery) of RCC with inferior vena cava (IVC) tumor thrombus.

Introduction. Prostate cancer (PСa) is one of the most common malignant diseases in men in the world. Radical prostatectomy remains the «gold standard» for treating this pathology. Good long-term oncological results Active follow-up of low-risk patients, as well as modification of the Gleason scale, suggested the possibility of using AS in carefully selected patients with intermediate-risk PCa. The introduction of molecular genetic markers into practice will allow a personalized choice of a treatment method.

Introduction. Bladder cancer is the 10th most common cancer worldwide. Radical cystectomy remains the gold standard for muscle invasive bladder cancer. The active use of robot-assisted cystectomy for treating patients with bladder cancer allows considering it as an alternative surgical option. The review is aimed at collecting and systematizing the evidence base for intracorporeal robot-assisted cystectomy.

Introduction. Information about the brachytherapy-induced immune reactions, which can be used for therapeutic purposes, is of great clinical value.

Introduction. Prostate cancer is one of the most common oncological diseases in men. Robot-assisted radical prostatectomy is associated with better urinary continence, compared with open and laparoscopic technique. Their oncologic outcomes are comparable. However, urinary incontinence after this surgery remains a challenge.

Aim. To present a new technique of anterior reconstruction of pelvic structures during robot-assisted radical prostatectomy and evaluate its efficacy and safety.

Introduction. It has been established that prolonged androgen-deprivation therapy (ADT) of prostate cancer leads to a decrease in bone mineral density (BMD) and increases the risk of fractures, which is an important medical and social problem. Zoledronic acid (ZA) is most often used for the prevention of osteoporosis against the background of ADT.

Introduction. Minimally invasive radical cystectomy replicates principles of open surgery and has similar oncological outcomes. In addition, it may reduce the incidence of early postoperative complications and confer earlier patients’ recovery.

Introduction. Glansectomy is one of the organ-sparing surgeries for localized penile cancer (PC) treatment. Glanuloplasty with urethral flap was made to achieve good cosmetic results. Unfortunately, this method is inevitably leads to micropenia, and therefore penile elongation should be considered as a component of the complex treatment. We have presented the outcomes of this treatment method in patient with PC.