Выпуск №1 за 2010 год

Radical prostatectomy – is one of the main methods of the treatment for prostate cancer. One of undecided is a problem of the possibility and practicability of the prostatectomy for locally advanced prostate cancer. Some authors recommend conservative (external beam or hormonal) treatment. Th e other studies demonstrate the advantage of the operative method for T3 tumors. Presented meta-analisis has shown that combination neoadjuvant hormonal therapy with surgery does not provide the statistical signifi cant advantage in clinical outcome.

In the process of the trial an attempt was made to evaluate approximate people audience, that try to fi nd solution of problems associated with urological health by using internet technologies. In the present trial open statistic which is provided by searching engines Yandex (www.yandex.ru), Rambler (www.rambler.ru), Google (www.google.com); data of statistical systems such as LiveInternet (www.liveinternet.ru), SpyLOG (rating. spylog.ru), Rambler's Top100 (top100.

Th e paper is dedicated to primary bladder reconstruction with local fl aps in children with exstrophy. An original method of bladder neck reconstruction with local fl aps with obligatory convergence of pubic bones in newborn infants has been proposed. 93 infants underwent surgery in the period from 1988 to 2009. Th e main group consisted of patients who underwent primary bladder reconstruction with local fl aps with convergence of the symphysis pubis bones (81). In 17 infants the procedure was supplied by the ileal osteotomy.

In the paper results of examination and treatment of 27 patients suff ering from recurrent phosphate nephrolithiasis which were treated at the Research Institute of Urology were analyzed. Patients with chronic renal failure grade II-III and hyperparathyroidism were excluded. Along with overall assessment of renal function (glomerular fi ltration rate, daily protein excretion, inorganic phosphate excretion etc.) and spectral analysis of excreted calculi, all patients underwent assessment for bone mineral density of calcaneal tuber by osteodensitometry using Calscan device (Lund, Sweden).

To evaluate the eff ects of Botulinum Toxin Type A (BTXA) injected into the external urethral sphincter in patients with dctrusorexternal sphincter dyssynergia caused by spinal cord injury. Th e eff ects of transurethral (TU) versus transperineal (TP) BTXA injection were compared. 17 male patients with detrusor-sphincter dyssynergia were divided into 2 groups: TU group and TP group. Four points injection method was employed with allocation by cystoscope in TU group. 1 point injection method percutaneous around the urethral was employed with allocation by digital rectal examination.

Increase of spacefl ight duration, long-term hermetic capacity projects together with challenges of health status maintenance and performance capability of test researchers raise a question about need for research of reproductive function under that condition. Data on eff ect of long isolation condition on male reproductive system status is extremely limited.

Trial for clinical effi cacy and safety of Selzinc Plus (Pro.Med.CS Praha), comprising selenium, zinc, vitamins A, E and C in patients with chronic non-infectious prostatitis grade IIIA with fertility disorder was performed at the Research Institute of Urology. Th e drug eff ect on time course of patient spermogram parameters was examined. Also selenium concentration measurement in main and control groups was carried out.

An open comparative study was performed at the Research Institute of Urology to examine sensibility and safety of technetium-labeled zoledronic acid drug Rezoscan,99mTc in patients with prostate cancer in case of skeletal lesions detected by bone scanning. Frequency of coincidence and discrepancy in bone scanning results when utilizing Rezoscan, 99mTc or Technifor, 99mTc was evaluated. Novel drug safety was assessed by virtue of analysis of undesirable events and side eff ects frequency.

In despite of achievements in different types of urine derivation, the estimation of life' quality in patients underwent of such type of operative treatment still be not only the medical problem, but more social one. Th ere were estimated retrospectively 148 patients with bladder cancer, 145 patients underwent of radical cystectomy and urine derivation. Patients were divided into groups by type of urine derivation. Th e fi rst group included 66 patients aft er incontinential form of urine derivation – ileum conduit (Briker operation).