Number №1, 2019 - page 102-106

Influence of varicocele on the hormonal background and the reproductive system of men DOI: 10.29188/2222-8543-2019-11-1-102-106

Efremov E.A., Shehovcev S.Yu., Butov A.O, Kastrikin Yu.V., Kozdoba A.S., Garaev T.I.
Information about authors:
  • Efremov E.A. – Dr. Sc., Professor of the Department of Urology, Andrology and Oncourology of Russian National Research Medical University named aer N.I. Pirogov of the Ministry of Health of Russia, Head of the Department of Andrology and Human Reproduction of N. Lopatkin Research Institute of urology and Interventional Radiology – branch of the National Medical Research Centre of Radiology of Ministry of health of Russian Federation, e-mail: konfandrology@rambler.ru; 
  • Shekhovtsov S.Yu. – Dr. Sc., Head of the Department of Urology, Andrology and Oncourology of Russian National Research Medical University named aer N.I. Pirogov of the Ministry of Health of Russian Federation, e-mail: Shehoff@mail.ru
  • Butov A.О. – Postgraduate Student, Department of Urology, Andrology and Oncourology of Russian National Research Medical University named aer N.I. Pirogov of the Ministry of Health Russian Federation, e-mail: al_vasenov@mail.ru
  • Kastrikin Yu.V. – Postgraduate Student, Department of Urology, Andrology and Oncourology of Russian National Research Medical University named aer N.I. Pirogov of the Ministry of Health of Russian Federation, e-mail – yurii_kn@mail.ru; 
  • Kozdoba A.S. – PhDs, Associate Professor of the Department of Urology, Andrology and Oncourology, of Russian National Research Medical University named aer N.I. Pirogov of the Ministry of Health of Russia e-mail –akozdoba@mail.ru
  • Garayev T.I. – clinical intern of N.A. Lopatkin Scientific Research Institute of Urology and Interventional Radiology – Branch of the National Medical Research Radiological Centre of the Ministry of Health of Russian Federation, e-mail: drturalqarayev@mail.ru
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Varicocele is one of the most common diseases in men of reproductive age, and also the cause of male infertility. A lot of work has been devoted to the study of varicocele, but its impact on the functioning of the male reproductive system is still a subject of debate. There are both single studies and larger comparative studies devoted to the evaluation of the effect of varicocele on the hormonal background and reproductive system of a man. Most of these studies demonstrate the negative impact of varicocele on male development, the hormonal profile and the possibility of paternity.

Attention is drawn to the fact that patients with a preoperatively normal hormonal profile did not have a statistically significant change in the hormonal background, but a tendency to increase testosterone levels was revealed. There was also a statistically significant improvement in spermogram parameters. Thus, varicocele has a negative impact on the hormonal ackground and the reproductive system of men.

Authors declare lack of the possible conflicts of interests

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varicocele, testosterone, hormonal profile, spermatogenesis, the reproductive system of a man, microsurgical varicocelectomy

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