Objectives. The aim of the study was to evaluate the clinical outcomes, complications and quality of life issues after the surgical treatment of pelvic organ prolapse (POP) with the use of the modern minimally invasive techniques.

Materials and methods. Clinical outcomes were assessed in 376 female patients with POP treated using “Prolift” (total, anterior, posterior) and “Prolift+M” (total, anterior, posterior). POP severity was assessed quantitatively using POP-Q. Quality of life was assessed using PFIQ-7. Median follow-up was 52 months (range 6-110 months).

Results. Intraand early postoperative complications occurred in 6.4%, 5.8% and 5.7% of Prolift (Prolift+M) total, Prolift (Prolift+M) anterior and Prolift (Prolift+M) posterior cases, correspondingly. Quality of life was significantly better by the end of first month after the operation and was at the highest point at month 6 without further deterioration. Late complications were detected in 8.5% of cases with recurrence in 3.7% of patients. In general, improvement was detected for all POP-Q single parameters. Overall efficacy for POP correction (96,3%) and complication rate in our clinic are among the best in the world.

Conclusions. Based on the big volume of operations and long follow-up data we were able to show the high rate of POP full correction in female patients with the use of mesh transplants. One of the necessary prerequisites for such a success – implementation of these operations in the high volume clinical center.