Introduction. Prostatic lithiasis complicates the courses of prostatitis and benign prostatic hyperplasia. The aim of the study is to evaluate the effectiveness of complex treatment of patients with chronic prostatitis (CP) associated with prostate stones by combining extracorporeal shock wave therapy (ESWT) with a phytotherapeutic drug Canephron.

Study design. This is an open prospective randomized comparative study.

Materials and methods. 73 patients with CP (stage IIIA) and prostate stones were subdivided into three groups. Patients from the first group (n=22) had been receiving Canephron for one month; patients from the second group (n=23) underwent 8 sessions of ESWT (Aries Dornier). Patients from the third group (n=28) had been receiving ESWT combined with phytotherapy. The effectiveness of the treatment was evaluated a?er its end and three months later.

Results. Canephron monotherapy has not demonstrated any litholytic effect but it has lowered the intensity of inflammation by 65,2%, reduced urination disorders twofold, improved the quality of life by one third and lowered the intensity of pain. The maximum and mean values of urine flow rate have been increased by 29.4% and 22.9%, respectively. Further pain reduction was observed three months after the monotherapy. ESWT monotherapy has demonstrated a lowered therapeutic effect: the intensity of pain has been lowered by 11.9% and urination has been improved by 37.2%. The volume of the prostate has been reduced by 11.3% and the severity of prostatic lithiasis by 16.7%. Three months later, the intensity of pain has been reduced by 69.6%, urination disorders – by 55.8% and the severity of prostatic lithiasis has been reduced almost twice. Combined therapy appeared to be the most effective. Three months later, prostate secretions have been sanitated in 67.9% of patients from the third group. ?e intensity of pain has been reduced by 86.7%, the degree of urination disorders – by 65.2% and the severity of prostatic lithiasis – by 60.9%.

Conclusions. Complex application of Canephron phytotherapy combined with ESWT appeared to be the most effective in treating patients with CP (stage IIIA). Primary results demonstrate a significant improvement only for several parameters; the final effect should be evaluated only three months after the therapy.

Authors declare lack of the possible conflicts of interests.