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Erectile dysfunction in patients with liver cirrhosis DOI: 10.29188/2222-8543-2022-15-2-104-109
- Mechik V.S. – urologist, City Clinical Hospital named after D.D. Pletnev; Moscow, Russia
- Efremov E.A. – Dr. Sc., Professor of the Department of Urology, Andrology and Oncology of Pirogov Russian National Research Medical University; Head of the International Center for Andrology; Moscow, Russia; https://orcid.org/0000-0001-7193-7413
- Monakhov D.V. – PhD, Associate Professor of the Department of Faculty Surgery of the Pediatric Faculty of Pirogov Russian National Research Medical University; surgeon of City Clinical Hospital named after D.D. Pletnev; Moscow, Russia; https://orcid.org/0000-0001-7303-2087
- Kasatonova E.V. – researcher of N.A. Lopatkin Scientific Research Institute of Urology and Interventional Radiology – Branch of the National Medical Research Centre of Radiology of the Ministry of Health of Russian Federation; Moscow, Russia; https://orcid.org/0000-0003-3279-2682
- Kaprin A.D. – Dr. Sc., professor, academician of RAS, general director of the National Medical Research Centre of Radiology of Ministry of health of Russian Federation, director of P.A. Herzen Institution, Head of Department of Oncology and Radiology named after V.P. Kharchenko RUDN University; Moscow, Russia; https://orcid.org/0000-0001-8784-8415
485 Introduction. In this literature review we discuss the etiology, risk factors, and features of erectile dysfunction management in men with liver disease and cirrhosis.
Materials and methods. A search to identify original articles and reviews in PubMed, еLibrary, ScienceDirect, Scopus, EMBASE databases suitable for the purposes of this review was conducted by combining the following terms: «hepatitis», «liver disease», «cirrhosis», «erectile dysfunction», «sexual dysfunction» in Russian and English.
Results. Clinically significant erectile dysfunction in liver disease can be detected in more than half of patients with cirrhosis, but usually elude the attention of doctors and researchers. Although erectile dysfunction is not a life-threatening disorder, its impact on quality of life is important. Patients with cirrhosis often suffer from comorbidities that are also known to be involved in the etiopathogenesis of sexual dysfunction. While treating ED in cirrhotic patients is a clinical challenge, almost all studies are epidemiological or assess risk factors.
Conclusions. The variety of symptoms and the significant deterioration in the quality of life need a multidisciplinary approach and timely intervention. There is a need to evaluate the quality of sexual life in men as part of the examination protocol for liver disease.
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