Contacts: Shcherbinin Sergey Nikolaevich, 3678344@mail.ru

Introduction. Computed tomography (CT) imaging, including contrast studies, is being more commonly used for diagnostics of urinary tract conditions. Contrast agent (CA) iopromide deserves special attention for use in indirect abdominal CT-aortography. Aim. This study generalizes N.A. Lopatkin Urology Research Institute experience of using iopromide agent for indirect abdominal CT-aortography (IACA).

Materials and methods. During 2010-2018 in N.A. Lopatkin Urology Research Institute 2625 indirect abdominal angiographies were performed, and we assessed efficacy and safety of iopromide CA (Ultravist®) in different categories of urological patients.

Results. Using iopromide in 300 and 370 mg of iodine per ml concentration excellent and goof quality images were obtained, which caused no difficulties for interpretation, and good tolerability was noted. iopromide was well tolerated by urological patients of all age groups. Only 42 (1,6%) patients noted flushing which resolved within 1-2 minutes, and 5 (0,19%) had vomiting during injection of CA, which quickly resolved by itself after stopping the injection. Even in patients with transplanted kidney iopromide didn’t cause significant change in serum creatinine and urea concentration within 7 days after IACA. Patients with chronic kidney disease being on hemodyalisis and patients with transplanted kidneys had no adverse reactions related to administration of this CA.

Conclusion. Iopromide has proven efficacy and safety in real clinical practice for indirect abdominal CT-aortography in work-up among all categories of urological patients, including elderly men and patients with chronic kidney disease.

For citation: Shcherbinin S.N., Tokareva E.V., Sivkov A.V. Indirect abdominal CT aortography with low osmolar radiopaque iopromide in urological patients: experience in the use. Experimental and clinical urology 2019;(3):191-196