Frequency and nature of symptoms of dysfunction of the lower urinary tract in persons over 40 years old
Postcoital cystitis as a cause of sexual dysfunction in women
A modern view on the screening of urolithiasis
Hereditary factor of metaphylaxis of urolithiasis
Treatment of infertility associated with a high level of sperm DNA fragmentation
COVID-19 associated encrusting cystitis
Endoscopic correction of vesicoureteral reflux in children: differentiated choice of method, material and dosage
Male infertility in the Russian Federation: statistics for 2000-2018
Evaluation of the effectiveness of perineum muscle training in restoring erectile function
Epidemiology of urolithiasis in the Perm region: results of a 30-year study
The economic and economic rationale for the use of modern methods of treating urolithiasis
Incidence of ICD in the Russian Federation (2005-2016)
Screening for prostate cancer: modern presentation and organization
Primary multiple transitional cell epithelium
Androgenic screening in men over 50 years
The role of stem cells in the treatment of urinary incontinence
Percutaneous nephrolithotripsy in infected urine
Testicular Prosthesis in Children and Adolescents: Results from a Multicenter Study
Premature ejaculation is the current state of the problem.
Alternative methods of treatment of localized prostate cancer
Partial doubling of the urethra: paraurethral motion
Comparative review of disposable flexible ureteronephroscope
The prevalence of symptoms of impairment of the function of the lower urinary tract in men according to the results of a population study
Patient-centered system of organization of medical care in urology using...
Radioisotope lymphoscintigraphy with PCa
Metabolic risk factors and formation of urinary stones
Ureteral amputation in the performance of contact ureterolithotrypsy
Principles of «4P Medicine» in the organization of health care in the context of urological diseases
Changes in the electrolyte composition of urine under the influence of sodium hypochlorite. The possibility
of reducing the risk of recurrence of nephrolithiasis
The analysis of the accuracy of factors for the survival predictiry after radical cystectomy
Citokine status in pathients with recurrent urinary tract infection
The role of distance education in improving primary health care professionals.
Comparative analysis of the results of cancer radical retropubic and robot-assisted prostatectomy.
Experience of clinical and economical treatment cancer patients
Comparison of analysis details for open, laparoscopic
and robot-assisted nephrectomy in the..
First results of standardized programme for BPH diagnosis and treatment
Evaluation of serum Chromogranin A levels in different prostatic diseases
Retarded ejaculation is a rare diagnosis
Clinical and economic analysis of the surgical treatment of prostate cancer
Brachytherapy prostate cancer: postimplantnaya dosimetry and dependence ...
Simulation prostatic carcinogenesis
New volume-forming drug for the treatment of stress urinary incontinence based on poly-ε-caprolactone particles DOI: 10.29188/2222-8543-2019-11-1-18-23
Ismailova A.M. – assistant scientist of the Branch of the M.M. ShemyakinYu.A. Ovchinnikov Institute of Bioorganic Chemistry of the Russian Academy of Sciences; e-mail: ismailowa.a.m@yandex.ru; ORCID 0000-0003-33162-0141
Makarov A.V. – PhD, Senior Researcher of the National Medical Research Center for Obstetrics, Gynecology and Perinatology named aer Academician V.I. Kulakov of Ministry of Healthcare of Russian Federation and assistant professor of Pirogov Russian National Research Medical University, Ministry of Healthcare of Russian Federation; e-mail: anvitmak@yandex.ru; ORCID 0000-0003-2133-2293
Tukhovskaya E.A. – PhD, scientist of the Branch of the M.M. ShemyakinYu.A. Ovchinnikov Institute of Bioorganic Chemistry of the Russian Academy of Sciences, e-mail: tukhovskaya@bibch.ru; ORCID 0000-0001-6174-4052
Belous G.I. – assistant scientist of the Branch of the M.M. ShemyakinYu.A. Ovchinnikov Institute of Bioorganic Chemistry of the Russian Academy of Sciences; e-mail: egor-belous91@yandex.ru
Apolikhina I.A. – Dr. Sc., Head of the Department of Aesthetic Gynecology and Rehabilitation of the National Medical Research Center for Obstetrics, Gynecology and Perinatology named aer Academician Kulakov V.I. of Ministry of Healthcare of Russian Federation; е-mail: apolikhina@inbox.ru
Saidova A.S.– Ph.D., obstetrician-gynecologist of the Department of Aesthetic Gynecology and Rehabilitation of the National Medical Research Center for Obstetrics, Gynecology and Perinatology named aer Academician V.I. Kulakov of Ministry of Healthcare of Russian Federation, e-mail: asekova14@yandex.ru; ORCID 0000-0003-3473-3109
Bogorodsky S.E. – Researcher of the Federal Scientific Research Centre “Crystallography and Photonics” of Russian Academy of Sciences, e-mail: bogens2@email.ru
Arutyunyan I.V. – PhD, senior researcher of the National Medical Research Center for Obstetrics, Gynecology and Perinatology named aer Academician V.I. Kulakov of Ministry of Healthcare of Russian Federation and Research Institute of Human Morphology, e-mail: labrosta@yandex.ru ORCID: 0000-0002-4344-8943
Elchaninov A.V. – Dr. Sc., senior researcher of the National Medical Research Center for Obstetrics, Gynecology and Perinatology named aer Academician V.I. Kulakov of Ministry of Healthcare of Russian Federation and Research Institute of Human Morphology, e-mail: elchandrey@yandex.ru; ORCID 0000-0002-2392-4439
Lokhonina A.V. – assistant scientist of the National Medical Research Center for Obstetrics, Gynecology and Perinatology named aer Academician V.I. Kulakov of Ministry of Healthcare of Russian Federation and Research Institute of Human Morphology, e-mail: nastya.serbsky@gmail.com; ORCID 0000-0001-8077-2307
Nikitina M.P. – researcher of Research Institute of Human Morphology, e-mail: mary.krutikova@gmail.com
Popov V.K. – Dr. Sc., head of the laboratory of Federal Scientific Research Centre “Crystallography and Photonics” of Russian Academy of Sciences, e-mail: popov@laser.ru; ORCID 0000-0002-9305-6964
Bicherova I.A. – PhD, assistant professor of Pirogov Russian National Research Medical University, Ministry of Healthcare of Russian Federation, e-mail: norav1@yandex.ru
Fatkhudinov T.Kh. – Dr. Sc., head of the laboratory of National Medical Research Center for Obstetrics, Gynecology and Perinatology named aer Academician V.I. Kulakov of Ministry of Healthcare of Russian Federation and Research Institute of Human Morphology, e-mail: fatkhudinov@gmail.com; ORCID 0000-0002-6498-5764
1307
The development of new methods and minimally invasive technologies for treating stress urinary incontinence in women is one of the most urgent problems of modern gynecology. Тhe promising approaches is the use of periurethral administration of bulking agents that create additional volume in the field of transplantation and aimed at achieving an equilibrium pressure between the bladder and urethra. Thus bulking agents are capable for reducing the frequency of intra-and post-operative complications, as well as ensuring the most effective rehabilitation of patients
Bulking agent based on polycaprolactone particles obtained by the supercritical fluid method is proposed. This agent was compared with SUI Urodex® in an experimental model of stress urinary incontinence in in female SD rats
The analysis of the results showed that the bulking agent based on polycaprolactone particles hasthe same high efficiency in the treatment of urinary incontinence. The urodynamic index of LPP of a newbulking agent based on polycaprolactone particlesis comparable to that for SUI Urodex®. Bulking agent based on polycaprolactone particles presumably hasseveral advantages:such as a longertherapeutic effect(about 3 years) due to slow biodegradation in the body, lower cost pharmacological market due to production in Russia.
Authors declare lack of the possible conflicts of interests.
5-year impact factor of Russian science citation index from 15.01.2020 - 0,723
10-year H-index 21
Included in the Russian Science Citation Index (RSCI)
ISSN print 2222-8543 ISSN online 2712-8571
The journal is included in the List of Russian peer-reviewed scientific journals which should publish the main scientific results of dissertations for the degrees of Doctor and PhD of sciences
Поиск
International Classification
Сайт журнала "Экспериментальная и клиническая урология" содержит материалы
медицинского характера, предназначенные исключительно для работников
здравоохранения.
Подтвердите, пожалуйста, что Вы являетесь медицинским работником с соответствующим
дипломом или студентом медицинского образовательного учреждения.