Development of laboratory technology for obtaining the cellular (erythrocyte) form of ceftriaxone and experimental substantiation of the feasibility of its use in non-obstructive pyelonephritis
Introduction. Ceftriaxone is an effective cephalosporin antibiotic, but its use can lead to undesirable effects. Directed transport of drugsreducesthese effects, the therapeutic dose of the drug and the frequency of administration. Aim. To develop a ceftriaxone delivery system using erythrocyte vectors for non-obstructive pyelonephritis to selectively affect the organ in order to increase its efficiency and reduce toxicity