Баныра О.Б.

In this review article we have analyzed the results of major contemporary investigations that concern kidney cancer biomarkers searching. Thanks to the new scientific achievements in fields of genetics, molecular biology, biochemistry and by using of novel diagnostic technologies it became possible to determine cancerspecific components concentrations in tissues and biological fluids.

Angiogenesis Inhibition in Renal Cell Carcinoma (RCC) Treatment: Mechanisms, Especialities and Perspectives O.B. Banyra, A.V. Shulyak Renal cell carcinoma is a widespread oncourologic pathology with a tendention to increasing of morbidity. Surgery is a general method of its treatment. During last years approaches to medical treatment RCC, especially metastatic forms, have changed in principle. It has been proved the major role of von-Hippel Lindau gene mutations and angiogenesis in RCC development.

Fournier's Gangrene is a fulminating spontaneous necrosis of scrotum. Necrotic process can hit genitalia, peritoneum. Traumatic and infectious etiology. Manifestation is after 2 7 days: acute pain in scrotum, necrosis symptoms. Lethality rates up to 30 40%, directly proportional to affected area. In case of testis involvement lethality rates raise up to 60 90%.