Савватеева М.В.

Introduction. 30 years ago, the PSA test made a radical change in prostate cancer diagnostics. However, today there is hard data indicating its limited diagnostic relevance of this marker. A search for new markers of prostate cancer and development of test systems on their basis is becoming relevant.

At present time the challenge of prostate cancer early detection becomes more and more vital due to prostate cancer (PCa) is one of the most common malignant tumors in males. Development and clinical introduction of programs of prostate cancer early detection is not only about a medical concern but about social and economic meaning for government. After introduction 20 years ago PSA test gave a start to early prostate cancer detection era, increased rate of localized curable cancer detection.