Introduction. Low adherence treatment is one of the reasons for the failure of the treatment of chronic diseases, including urolithiasis. The main efforts to increase patients' adherence to treatment should be aimed at acquiring knowledge about possible complications and prognosis of the course of the disease, as well as about the main methods of diagnosis and treatment. However, there is currently no tool to comprehensively assess the initial level of knowledge in these matters and thereby determine the level of adherence to the treatment of urolithiasis.

Materials and methods. On the basis of N. Lopatkin Sciantific Research Institute of Urology and Interventional Radiology conducted a study to study the adherence of patients to the metaphylaxis of urolithiasis. The study involved 183 patients (78 men and 105 women). The mean age of the participants was 50.39±0.96 years. The study was conducted on the basis of data obtained using a specially designed questionnaire that allows determining risk factors for the development of urolithiasis, patients' knowledge of anti-relapse treatment of urolithiasis and their readiness for metaphylaxis of urolithiasis.

Statistical data processing was carried out using computer programs Statistica 10.0 (StatSoft, USA) and MedCac 13.0 (USA) using parametric methods: descriptive statistics, chi-square and chi-square for the trend.

Results. Women are the most informed in matters of urolirthisis metaphylaxis. However, only 15.8% of patients with urolithiasis, regardless of gender, know nutritional recommendations to reduce the risk of recurrence of stone formation. 67.2% of the respondents lacked knowledge about the pH and density of urine, as well as the importance of their control and correction. Almost all participants in the study noted their willingness to change their lifestyle to prevent recurrence of stone formation. however, women attach more importance to the metaphylaxis of kidney stone desease.

Conclusions. Assessment of adherence to KSD metaphylaxis is an important component in reducing the frequency of stone formation recurrence, improving the prognosis of the course of the disease, as well as improving the quality of life of patients. the observed lack of patient knowledge of risk factors requires increased health education. The development and implementation in practice of a personal approach to metaphylaxis, taking into account the factors we have discovered, can improve adherence to the treatment of urolithiasis.