Number №4, 2020 - page 76-81

Correction of symptoms of impaired urination in men with the drug Diunorm ® DOI: 10.29188/2222-8543-2020-13-4-76-80

For citation: Shkodkin S.V., Polischuk A.V., Chirkov S.V., Churikova O.V., Kravtsova N.A. Correction of symptoms of impaired urination in men with the drug Diunorm®. Experimental and Clinical Urology 2020(4):76-80, https://doi.org/10.29188/2222-8543-2020-13-4-76-80
S.V. Shkodkin, A.V. Polischuk, S.V. Chirkov, O.V. Churikova, N.A. Kravtsova
Information about authors:
  • Shkodkin S.V. – MD, PhD, Department of Hospital Surgery Professor of the Medical Institute Federal State Autonomous Educational Institution of Higher Education «Belgorod National Research University», urologist Belgorod Regional Clinical Hospital of Svyatitelya Ioasafa; Belgorod, Russia; https://orcid.org/0000-0003-2495-5760
  • Polischuk A.V. – assistant Department of Hospital Surgery Professor of the Medical Institute Federal State Autonomous Educational Institution of Higher Education «Belgorod National Research University», urologist medical center «Fomin Clinic»; Belgorod, Russia; https://orcid.org/0000-0001-5164-7128
  • Chirkov S.V. – post-graduate student Department of Hospital Surgery Professor of the Medical Institute Federal State Autonomous Educational Institution of Higher Education «Belgorod National Research University», urologist St. Luke of Crimea distrct hospital, Stariy Oskol, Belgorod region; Belgorod, Russia; https://orcid.org/0000-0002-5828-1664
  • Churikova O.V. – post-graduate student Department of Hospital Surgery Professor of the Medical Institute Federal State Autonomous Educational Institution of Higher Education «Belgorod National Research University», urologist medical center «Promedica»; Belgorod, Russia; https://orcid.org/0000-0003-1410-5017
  • Kravtsova N.A. – urologist of the medical centre «Energy of Life»
92

Introduction. Lower urinary tract symptoms are a socially significant problem on a global scale.

Material and methods. The clinical study included 57 men with complaints of LUTS. Patients were randomized to receive LUTS medication. The main observation group consisted of 42 primary patients aged 41 to 67 years. For therapy in whom the drug Diunorm® was used at a dose of 400 mg once a day. The control group included 15 patients aged 50 to 64 years. As an initial therapy, Tamsulosin 0.4 mg was prescribed once a day. The observation period last 90 days in both groups. The effectiveness of therapy was assessed on the basis of questionnaire scales, ultrasound and uroflowmetry.

Results and discussion. Conservative therapy of LUTS in both groups was accompanied by a subjective reduction in symptoms according to the total score on the IPSS scale (p <0.0001). A similar dynamics in the study groups took place in relation to a decrease in the frequency of nocturia (p <0.01). Analysis of the IIEF-5 questionnaire and ultrasound did not reveal any changes in the observation groups for 3 months (p> 0.05). A significant increase in the maximum urination rate was recorded in patients taking Diunorm®. The growth rate was on average 29.3 ± 21.0% (p <0.001).

Conclusion. The drug Diunorm® reliably and comparable to tamsulosin reduces the severity of LUTS and the frequency of nocturia in primary relatively young patients, without causing ejaculatory disorders.

AttachmentSize
Download938.24 KB
lower urinary tract symptoms, LUTS, benign prostatic hyperplasia, BPH.

Readera - Социальная платформа публикаций

Crossref makes research outputs easy to find, cite, link, and assess