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Correction of symptoms of impaired urination in men with the drug Diunorm ® DOI: 10.29188/2222-8543-2020-13-4-76-80
For citation:
Shkodkin S.V., Polischuk A.V., Chirkov S.V., Churikova O.V., Kravtsova N.A. Correction of symptoms of impaired urination in men with the drug Diunorm®. Experimental and Clinical Urology 2020(4):76-80, https://doi.org/10.29188/2222-8543-2020-13-4-76-80
Shkodkin S.V. – MD, PhD, Department of Hospital Surgery Professor of the Medical Institute Federal State Autonomous Educational Institution of Higher Education «Belgorod National Research University», urologist Belgorod Regional Clinical Hospital of Svyatitelya Ioasafa; Belgorod, Russia; https://orcid.org/0000-0003-2495-5760
Polischuk A.V. – assistant Department of Hospital Surgery Professor of the Medical Institute Federal State Autonomous Educational Institution of Higher Education «Belgorod National Research University», urologist medical center «Fomin Clinic»; Belgorod, Russia; https://orcid.org/0000-0001-5164-7128
Chirkov S.V. – post-graduate student Department of Hospital Surgery Professor of the Medical Institute Federal State Autonomous Educational Institution of Higher Education «Belgorod National Research University», urologist St. Luke of Crimea distrct hospital, Stariy Oskol, Belgorod region; Belgorod, Russia; https://orcid.org/0000-0002-5828-1664
Churikova O.V. – post-graduate student Department of Hospital Surgery Professor of the Medical Institute Federal State Autonomous Educational Institution of Higher Education «Belgorod National Research University», urologist medical center «Promedica»; Belgorod, Russia; https://orcid.org/0000-0003-1410-5017
Kravtsova N.A. – urologist of the medical centre «Energy of Life»
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Introduction. Lower urinary tract symptoms are a socially significant problem on a global scale.
Material and methods. The clinical study included 57 men with complaints of LUTS. Patients were randomized to receive LUTS medication. The main observation group consisted of 42 primary patients aged 41 to 67 years. For therapy in whom the drug Diunorm® was used at a dose of 400 mg once a day. The control group included 15 patients aged 50 to 64 years. As an initial therapy, Tamsulosin 0.4 mg was prescribed once a day. The observation period last 90 days in both groups. The effectiveness of therapy was assessed on the basis of questionnaire scales, ultrasound and uroflowmetry.
Results and discussion. Conservative therapy of LUTS in both groups was accompanied by a subjective reduction in symptoms according to the total score on the IPSS scale (p <0.0001). A similar dynamics in the study groups took place in relation to a decrease in the frequency of nocturia (p <0.01). Analysis of the IIEF-5 questionnaire and ultrasound did not reveal any changes in the observation groups for 3 months (p> 0.05). A significant increase in the maximum urination rate was recorded in patients taking Diunorm®. The growth rate was on average 29.3 ± 21.0% (p <0.001).
Conclusion. The drug Diunorm® reliably and comparable to tamsulosin reduces the severity of LUTS and the frequency of nocturia in primary relatively young patients, without causing ejaculatory disorders.
5-year impact factor of Russian science citation index from 15.01.2020 - 0,723
10-year H-index 21
Included in the Russian Science Citation Index (RSCI)
ISSN print 2222-8543 ISSN online 2712-8571
The journal is included in the List of Russian peer-reviewed scientific journals which should publish the main scientific results of dissertations for the degrees of Doctor and PhD of sciences
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