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Number №1, 2024 - page 86-93

Mixed epithelial and stromal tumor in combination with oncocytoma of the kidney: a rare clinical case and review of the literature DOI: https://doi.org/10.29188/2222-8543-2024-17-1-86-93

For citation: Grebenkin E.V., Koshmelev A.A., Mono P.O., Baranova E.O., Pasechnik D.G., Fedotov V.V., Epishkina A.A., Shved N.V. , Zhivov A.V. Mixed epithelial and stromal tumor in combination with oncocytoma of the kidney: a rare clinical case and review of the literature. Experimental and Clinical Urology 2024;17(1):86-93; https://doi.org/10.29188/2222-8543-2024-17-1-86-93
Grebenkin E.V., Koshmelev A.A., Mono P.O., Baranova E.O., Pasechnik D.G., Fedotov V.V., Epishkina A.A., Shved N.V., Zhivov A.V.
Information about authors:
  • Grebenkin E.V. – PhD, Pathologist, LLC «UNIM», senior Lecturer at the Department of Fundamental Medicine National Research Nuclear University MEPhI; Moscow, Russia; RSCI Author ID 1017673, https://orcid.org/0000-0002-4990-6722
  • Koshmelev А.А. – PhD, urologist, «Ilyinsky hospital» JSC; Moscow, Russia; RSCI Author ID 636474, https://orcid.org/0000-0002-7736-6030
  • Monod P.O. – Dr. Sci., urologist, head of the urology department, «Ilyinsky hospital» JSC; Moscow, Russia; https://orcid.org/0009-0002-7074-5115
  • Baranova Е.О. – M.D., urologist, «Ilyinsky hospital» JSC; Moscow, Russia; https://orcid.org/0000-0002-3524-801X
  • Pasechnik D.G. – PhD, M.D., assistant professor; pathologist, LLC «UNIM»; Moscow, Russia; RSCI Author ID 637030, https://orcid.org/0009-0009-6216-2818
  • Fedotov V.V. – M.D., pathologist, LLC «UNIM»; Moscow, Russia; RSCI Author ID 779399, https://orcid.org/0000-0002-9447-3292
  • Epishkina А.А. – PhD, pathologist, LLC «UNIM», assistant professor at the Department of Fundamental Medicine National Research Nuclear University MEPhI; Moscow, Russia; RSCI Author ID 892316, https://orcid.org/0000-0002-7824-7949
  • Shved N.V. – PhD, pathologist, head physician LLC «UNIM»; Moscow, Russia; RSCI Author ID 690228
  • Zhivov A.V. – PhD, Associate Professor, urologist, oncourologist, head physician «Ilyinsky hospital» JSC; Moscow, Russia; RSCI Author ID 1021560, https://orcid.org/0009-0009-6916-6328
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Introduction. Mixed epithelial and stromal tumors (MEST) of the kidney are rare neoplasms and, along with adult cystic nephroma, are grouped together called mixed epithelial and stromal tumors (World Health Organization Classification of Tumors of the Kidney, 2022). Clinically and radiologically, they mimic other cystic renal neoplasms, thus definitive diagnosis requires histological and immunohistochemical examination. Despite the benign course, MEST can undergo malignancy; isolated cases of recurrence have also been documented.

Clinical case. Patient X, 65 years old, underwent robot-assisted left-side partial nephrectomy for cystic formations of the left kidney with a hypervascular soft tissue component along the medial semicircle of one of the cysts. According to histological examination, MEST of the left kidney in combination with oncocytoma was diagnosed.

Conclusions. This article presents probably the first published case of MEST in combination with oncocytoma of the kidney.

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mixed epithelial and stromal tumor of the kidney; adult cystic nephroma; oncocytoma

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