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Number №2, 2021 - page 23-29

Primary-multiple synchronous malignant neoplasms renal pelvis and both ureters DOI: 10.29188/2222-8543-2021-14-2-23-29

For citation: Popov S.V., Guseynov R.G., Skryabin O.N., Peremyshlenko O.N., Perepelitsa V.V., Davydov A.V., Barkhitdinov R.S., Katunin A.S., Mirzabekov M.M. Primary-multiple synchronous malignant neoplasms renal pelvis and both ureters. Experimental and Clinical Urology, 2021,14 (2):23-29;
https://doi.org/10.29188/2222-8543-2021-14-2-23-29
Popov S.V., Guseynov R.G., Skryabin O.N., Peremyshlenko O.N, Perepelica V.V., Davydov A.V., Barhitdinov R.S., Katunin A.S., Mirzabekov M.M.
Information about authors:
  • Popov S.V. – Dr. Sc., Head Physician, St. Luke Clinic State Budgetary Health Institution of St. Pe- tersburg; Saint-Petersburg, Russia;  https://orcid.org/0000-0003-2767-7153
  • Guseynov R.G. – Head of the Urology Department No2 of St. Petersburg Clinical Hospital of St. Luke; Saint-Petersburg, Russia;  https://orcid.org/0000-0001-9935-0243
  • Skryabin O.N. – Dr. Sc., Professor, Chief Oncologist of St. Petersburg Clinical Hospital of St. Luke, Scientific Director of the Center for Endoscopic Urology and New Technologies; Saint-Petersburg, Russia; https://orcid.org/0000-0002-6664-2861
  • Peremyshlenko A.S. – PhD, head of the pathological department, St. Luke Clinic State Budgetary Health Institution of St. Petersburg; Saint-Petersburg, Russia; 
  • Perepelitsa V.V. – PhD, urologist, St. Petersburg State Budgetary Healthcare Institution Clini- cal Hospital of St. Lukе; Saint-Petersburg, Russia
  • Davydov A.V. – PhD, urologist of St. Petersburg Clinical Hospital of St. Luke; Saint-Petersburg, Russia;  https://orcid.org/0000-0003-3062-5119
  • Barkhitdinov R.S. – urologist of St. Petersburg Clinical Hospital of St. Luke; Saint-Petersburg, Russia; https://orcid.org/0000-0001-7580-6197
  • Katunin A.S. – urologist of St. Petersburg Clinical Hospital of St. Luke; Saint-Petersburg, Russia; https://orcid.org/0000-0003-3676-6246
  • Mirzabekov M.M. – urologist of St. Petersburg Clinical Hospital of St. Luke; Saint-Petersburg, Russia; httpss://orcid.org/0000-0001-5792-1589
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Introduction. Urothelial carcinoma of the upper urinary tract in Western countries of Europe and USA occurs in 1-2 cases per 100,000 populations. Nephroretrectomy remains the main method of treatment of this pathology, however, the role of organ-sparing surgeries increases with the bilateral localization of the tumor process. Due to the rarity of bilateral upper urinary tract lesions with urothelial cancer and the lack of data evaluating the results of organ-sparing surgeries in such situations, each clinical case is of interest.

Materials and methods. The article describes a case of surgical treatment of a patient with non-invasive papillary urothelial carcinomas of both ureters and the pelvis of the right kidney, which were manifested by macrohematuria.

Results. The diagnosis was confirmed by computer tomography (CT) and ureteroscopy with tumor biopsy, which revealed a neoplasm of the right kidney pelvis, multiple tumors of the distal part of the right ureter and a solitary neoplasm of the middle part of left ureter. The patient underwent laparoscopic nephrureterectomy on the right with transurethral resection of the bladder wall in the area of the mouth of the right ureter and endoscopic removal of the neoplasm in the middle third of the left ureter using laser energy. At the control examination 1,5 months after the surgical treatment, according to the results of CT, cystoscopy with biopsy of the bladder and ureteroscopy, as well as histological examination of the biopsies, no data for tumor growth were found. At CT 6 months after the surgery, no data for the recurrence of cancer were obtained.

Сonclusions. This clinical observation demonstrates the technical feasibility and oncological feasibility of using organ-preserving surgical treatment for bilateral localization of low-grade urothelial carcinoma.

Conflict of interest. The authors declare no conflict of interest.

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