19180
The inhibitors of the phosphodiesterase type 5 (iPDE-5) are today the first line agents for the therapy of the erectile dysfunction (ED). The data regarding their effect on the male fertility is controversial.
26917
Phosphodiesterase type 5 inhibitors (iPDE-5) are the first line medications for erectile dysfunction in men. Given that all of them are highly selective, nevertheless they can have effects on the other isoforms of phosphodiesterase (including type 11), which are located in different tissues. Some experimental works show that influence on PDE-11 could affect spermatogenesis. Nevertheless, there is no common opinion whether if fertility affected or not and how.
20559
Introduction: widespread introduction of radical prostatectomy (RPE) into clinical practice and particularly its nerve- sparing option resulted an appearance of a new type of sexual dysfunction. This type of sexual dysfunction has specific particularities of ethiology, pathogenesis, clinical presentation and treatment options. But still there are no generally accepted terminology and standards of obtaining and presentation of data on this topic. In addition, a number of terms used in description of data obtained by different authors is treated differently.
