Хазан П.Л.

Objective: The article presents a review of modern literature on the problem of chronic diseases of the bladder, including painful bladder syndrome/interstitial cystitis, recurrent lower urinary tract infection, chemical or radiation cystitis, the pathogenesis of which is associated with the same pathophysiological changes.

Cystitis is one of the most common urological diseases. Up to 40% of females that had bacterial cystitis have a recurrence in nearest 6 months. Management of relapsing infection of lower urinary tract is a hard challenge. Using of hyaluronic acid in treatment of recurrent infection of lower urinary tract is one of promising option. Disregenerative processes in urothelium could be a result of interstitial inflammation with glycosaminoglycans deficit.