Introduction. Cisplatin and Doxorubicin have pronounced toxic effects on spermatogenesis. Modeling of spermatogenesis disorders using these drugs can become convenient and relevant when conducting preclinical studies to assess the specific activity of new drugs for the treatment of toxic cases of...
Introduction. Presence of calculus in an enlarged isolated renal calyx requires endoscopic or percutaneous correction to remove the calculus and eliminate the cause of local urodynamic disorders. If the calyx is significantly enlarged or the parenchyma over the enlarged calyx is atrophied, the...
Introduction. Abdominal obesity has been considered an important risk factor for the development of urolithiasis in recent years. In this paper, we investigated the influence of the degree of obesity in patients with urolithiasis on metabolic parameters and the frequency of detection of urinary...
Introduction. Various forms of urolithiasis are associated with a number of disorders and diseases in the pathogenesis of which lipid metabolism plays a significant role.
Objective. To determine the stereotype of consumption of fats, saturated fatty acids and cholesterol by patients with calcium...
Introduction. Frequent problem in everyday urology practice is the management of patients with large ureteral stones and clinically significant residual fragments after PCNL of large or staghorn caliculi and ESWL as part of the subsequent "sandwich therapy". There are a lot of different...
Introduction. Retrograde intrarenal surgery (RIRS) increasingly used for upper urinary tract stones removal. According to the he Russian society of urologists guidelines RIRS considered as a first- and second-line option for kidney stones up to 2 cm. The main limitation for its widespread adoption...
Introduction. IgG4-associated diseases are a systemic immune-dependent pathology characterized by diffuse or focal infiltration of affected tissues by lymphocytes and plasma cells expressing IgG4, followed by the development of phlebitis and fibrosclerosis in the affected tissues. In extremely rare...
Introduction. Robot-assisted radical prostatectomy, due to its low morbidity and high precision technique, is rapidly taking a leading position among the methods of treatment of localized prostate cancer. At the same time, the requirements for functional results of this surgery are steadily...
Introduction. The search for new markers for early diagnosis of prostate cancer (PCa) is an urgent task. The most promising substrate for research are microRNAs.
Materials and methods. Study is based on the results of bioinformatic analysis of mRNA and microRNA sequencing of 184 PCa samples and 50...
Introduction. Prostate cancer occupies a leading position in the structure of oncological morbidity and mortality. Radical prostatectomy in various modifications still remains the "gold standard" in the treatment of non-metastatic forms of this pathology. However, despite a large number...