Introduction. The COVID-19 pandemic has also greatly impacted people's psychological well-being, increasing stress levels, as well as their lifestyle and well-being. Therefore, to maintain health, men should take multicomponent complexes that have a beneficial effect on various organs and systems (including reproductive), have an antioxidant effect and help normalize basic physiological processes in the body. In particular, such supplements can be used as a preconception preparation of a man for conception in a couple.

Objective. To evaluate the action of the antioxidant complex «AndroDoz Light» in a group of men in the framework of preconceptional preparation (for conception of a child by a sexual partner).

Materials and methods. The data of 30 men aged 23 to 48 years (the average age was 26.3 ± 5.4 years) preparing for conception with a sexual partner were analyzed in this paper. AndroDoz Light was used by men for 1 month: effervescent tablet dissolved in a glass of water (200 ml) once a day during or after meals. To everyone in addition to the spermogram, microbiological examination of the ejaculate, finger rectal examination of the prostate gland (pancreas), ultrasound examination (ultrasound) of the scrotum organs, microscopic examination of the pancreatic secretion (SPH), microscopic examination of the urethral smear and PCR diagnostics of sexually transmitted diseases (androflor) were performed. The concentration of testosterone in the blood, the level of zinc in the sperm plasma were determined. The assessment of the quality of life and sexual function of men was carried out on the IIEF-15 scale (International Index of Erectile Function) and on the NIH-CPSI scale.

Results. The multicomponent complex AndroDoz Light helps not only to increase male fertility, improving the functional state of the male reproductive system (qualitative and quantitative spermogram indicators) and morphological indicators: reduces the percentage of sperm with DNA fragmentation, but also improves copulatory function, and is an additional source of necessary nutrients for the male body.

Conclusion. The use of the multicomponent complex AndroDoz Light in men as part of the preconceptional preparation of a married couple for conception is accompanied by an improvement in both general well-being and the quality of men's sexual life in general, positively affects the qualitative and quantitative indicators of the spermogram and sperm DNA fragmentation. The results obtained allow us to recommend the use of the multicomponent complex AndroDoz Light in men in the absence of pronounced reproductive problems as part of the preconceptional preparation of a married couple for conception