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Number №1, 2023 - page 73-79

Urolithiasis and renal tubular acidosis DOI: 10.29188/2222-8543-2023-16-1-73-79

For citation: Anokhin N.V., Prosyannikov M.Yu., Golovanov S.A., Konstantinova O.V., Voytko D.A., Sivkov A.V. Urolithiasis and renal tubular acidosis. Experimental and Clinical Urology 2023;16(1):73-79; https://doi.org/10.29188/2222-8543-2023-16-1-73-79
N.V. Anohin, M.Yu. Prosyannikov, S.A. Golovanov, O.V. Konstantinova, D.A. Voytko, A.V. Sivkov
Information about authors:
  • Anokhin N.V. – PhD., senior researcher at the Department of urolithiasis of N. Lopatkin Scientific Research Institute of Urology and Interventional Radiology – Branch of the National Medical Research Radiological Centre; Moscow, Russia; RSCI Author ID 8807749; https://orcid.org/0000-0002-4341-4276
  • Prosyannikov M.Yu. – PhD, head of the department of N. Lopatkin Scientific Research Institute of urology and Interventional Radiology – branch of the National Medical Research Centre of Radiology of Ministry of health of Russian Federation; Moscow, Russia; RSCI Author ID 791050; https://orcid.org/0000-0003-3635-5244
  • Golovanov S.A. – Dr. Sc., head of clinical laboratory diagnostic group of scientific laboratory department, N. Lopatkin Scientific Research Institute of Urology and Interventional Radiology – Branch of the National Medical Research Centre of Radiology of the Ministry of Health of Russian Federation; Moscow, Russia; RSCI AuthorID 636685; https://orcid.org/0000-0002-6516-4730
  • Konstantinova O.V. – Dr. Sc., Chief Researcher at the Department of urolithiasis of N. Lopatkin Scientific Research Institute of Urology and Interventional Radiology – Branch of the National Medical Research Centre of Radiology of the Ministry of Health of Russian Federation; Moscow, Russia; RSCI Author ID 679965; https://orcid.org/0000-0002-2214-7543
  • Voytko D.A. – PhD, senior researcher of N. Lopatkin Scientific Research Institute of urology and Interventional Radiology – branch of the National Medical Research Centre of Radiology of Ministry of health of Russian Federation; Moscow, Russia; RSCI Author ID 942353; https://orcid.org/0000-0003-1292-1651
  • Sivkov A.V. – PhD, Deputy Director of N. Lopatkin Scientific Research Institute of Urology and Interventional Radiology – Branch of the National Medical Research Centre of Radiology of the Ministry of Health of Russian Federation; Moscow, Russia; RSCI Author ID 622663; https://orcid.org/0000-0001-8852-6485
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Introduction. Distal renal tubular acidosis (dRTA) is a rare cause of stone formation in urolithiasis patients according to the conventional wisdom in the urological community. At the same time prevalence of the incomplete dRTA in patients with idiopathic calcium stones is 16.8% (13.6% in men and 25.5% in women) according to the recent studies. Previously, we published a review article, which describes the features of the dRTA etiology and pathogenesis, and presents diagnostic and treatment algorithms. We consider it interesting to present a clinical case in continuation of the previous publication.

Clinical case. There are anamnesis data, results of laboratory and instrumental analysis of the patient Zh. with a urolithiasis and renal tubular acidosis are presented. The patient was prescribed a long course of conservative citrate and thiazide diuretics therapy. The patient managed to achieve normalization of the main parameters of blood and urine, stable remission of the disease against the background of ongoing therapy. Conclusions, patients with distal renal tubular acidosis and urolithiasis are quite common in the clinical practice of urologist. Timely diagnosis of the disease and the appointment of adequate therapy can improve the quality of patient's life and reduce the number of stone relapses.

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urolithiasis; renal tubular acidosis; causes of stone formation; metaphylaxis

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