Выпуск №1 за 2025 год

Introduction. To assess the prospects of using artificial intelligence (AI) for the diagnosis and treatment of prostate cancer (PCa) and to evaluate the impact of AI on treatment efficacy.

Materials and Methods. A systematic literature review was conducted using scientific databases based on key queries related to AI and PCa. Studies from the last 10 years were included.

Introduction. Aging is a complex biological phenomenon that encompasses all organs and systems of the human body, including the urinary system. The theory of inflammatory aging suggests that the senescence process is accompanied by the formation of chronic inflammation, activation of oxidative stress and the production of inflammatory or profibrotic cytokines, which ultimately leads to fibrotic tissue transformation and the development of functional organ deficiency and, in particular, plays a key role in age-associated bladder restructuring.

Introduction. One of the main methods of surgical treatment of premature ejaculation is a selective dorsal neurotomy, based on decreasing penile sensitivity by selective resection of its sensory nerves. This surgical procedure is a quite effective, but invasive and has a long recovery time. Nowadays we know is a less invasive procedure, named selective minimally invasive cryoablation of penile sensory nerves. The essence of the method is cooling the nerves to a temperature of minus 78°С with thin needle-like cryoprobe, which is inserted through the skin.

Introduction. Radiation injury of the bladder is a complication after therapeutic irradiation of the pelvic organs. The strategy of pharmacotherapy of such complications is currently unclear due to the small number of studies and unclear pathogenesis.

Purpose of the study – to study the effectiveness of the use of bovine bladder polypeptides in modeling radiation injury of the bladder in rats.

Introduction. Modern medicine is developing every year and increasingly touches upon the aspect of male infertility, which can be a harbinger of the patient's future health. Understanding the mechanisms that fertility is a window to health opens new opportunities for important studies devoted to interdependent physiological processes. Identifying healthy individuals at risk for future cardiovascular disease, diabetes or cancer may allow changing reproductive medical care by changing long-term surveillance and reducing risk.