Introduction. Obstruction of the upper urinary tract is a major problem in recent clinical urology because it has a significant level of morbidity in the population and serious medical and social consequences (azotemia, renal colic, infectious and inflammatory complications, pain, renal failure). Urolithiasis, oncourological and oncogynecological pathologies together constitute an big part in the structure of the general somatic morbidity, while acute and chronic obstruction of urinary tract is their most typical complication.

Purpose. To make a comparative assessment of the effect of various options for drainage of the upper urinary tract (JJ-stenting of the ureter, ureteral catheter, percutaneous nephrostomy) during their obstruction on the history of azotemia.

Materials and methods. Three hundred patients with urological diseases corresponding to the patient’s model were assessed: «Diagnosis: urolithiasis / oncourological pathology / gynecological oncology, co-incident with obstruction of the upper urinary tract, age 30-80 years.»

Results and discussion. After resolving obstruction of the upper urinary tract, the dynamics of azotemia in terms of both urea and creatinine can have statistically significant differences depending on the method of drainage used. In terms of normalization and the number of patients with completely resolved azotemia, the method of percutaneous puncture nephrostomy comes first, ureter catheterization is in last position, in- ternal ureter stenting is an «intermediate position».

Conclusions. The obtained results should be taken into account to deepen the fundamental pathogenetic ideas about the development of azotemia under the impact of obstruction of the upper urinary tract and its resolution under the influence of various drainage methods, as well as when choosing these methods in a specific clinical situation in subsequent comprehensive studies.

Conflict of interest. The authors declare no conflict of interest.