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Number №3, 2021 - page 150-155

Options for antibacterial prophylaxis of infectious complications of prostate biopsy. Review of international guidelines DOI: 10.29188/2222-8543-2021-14-3-150-155

For citation: Popov S.V., Orlov I.N., Chernysheva D.Yu., Topuzov T.M., Malevich S.M., Neradovsky V.A. Options for antibacterial prophylaxis of infectious complications of prostate biopsy. Review of international guidelines. Experimental and Clinical Urology, 2021;14(3):150-155; https://doi.org/10.29188/2222-8543-2021-14-3-150-155
Popov S.V., Orlov I.N., Chernysheva D.Yu., Topuzov T.M., Malevich S.M., Neradovskiy V.A.
Information about authors:
  • Popov S.V. – Dr. Sc., the head of the SPbGBUZ «St. Luke’s Clinical Hospital», professor of the urology department at the «Military Medical Academy named after S.M. Kirova», assistant professor of the urology department at the FGBOU VO «Saint-Petersburg State University, Medical Faculty»; Saint-Petersburg, Russia; https://orcid.org/0000-0003-2767-7153
  • Orlov I.N. – PhD, medical director of St. Luke’s Clinical Hospital, assistant lecturer at «NorthWestern State Medical University named after I.I. Mechnikov»; Saint-Petersburg, Russia; https://orcid.org/0000-0001-5566-9789
  • Chernysheva D.Yu. – PhD, urologist at the St. Luke’s Clinical Hospital; Saint-Petersburg, Russia; https://orcid.org/0000-0002-0469-7007
  • Topuzov T.M. – PhD, the head of the urology department at the St. Luke’s Clinical Hospital; Saint-Petersburg, Russia; https://orcid.org/0000-0002-5040-5546
  • Malevich S.M. – urologist at the St. Luke’s Clinical Hospital; Saint-Petersburg, Russia; https://orcid.org/0000-0002-9175-2261
  • Neradovskiy V.A. – urologist at the St. Luke’s Clinical Hospital; Saint-Petersburg, Russia; https://orcid.org/0000-0003-4113-0525
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Introduction. Amount of prostate biopsy procedures rises every year and up to 95% of cases of prostate biopsy is performed via transrectal approach. The incidence of infectious complications of transrectal prostate biopsy reaches up to 17%, while incidence of such complications of transperineal biopsy is about 1%. The majority of international clinical guidelines recommends for obligatory antibiotic prophylaxis prior to prostate biopsy of any approach, but the choice of antibiotic is still debatable. The aim of this review is to sum up the approaches of international urological guidelines to the antibiotic prophylaxis prior to prostate biopsy.

Materials and methods. We analyzed the search results in the scientific databases PubMed, Google Scolar, elibrary.ru for the queries «prostate biopsy», «antibacterial prophylaxis» and «guidelines».

Results. According to the recommendations of most professional communities, antibacterial prophylaxis of infectious complications of prostate biopsy can be carried out in various ways - once or for a long time, one- or two-component, empirically or on the basis of urine culture on microflora.

Conclusion. Despite the differences in the levels of sensitivity and resistance of coliform flora around the world, the clinical guidelines in most countries are uniform in terms of the choice of drugs to reduce the risk of developing infectious complications after prostate biopsy. Approaches to antibacterial prophylaxis after prostate biopsy differ only depending on the type of biopsy access.

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prostate biopsy; infectious complications; antibiotics prophylaxis

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