UROLITHIASIS

Introduction. The role of the organic matrix in urinary stones genesis in urolithiasis patients is still unclear. The presence of a large amount of protein in the urinary stones matrix suggests the participation of the protein matrix in lithogenesis. Research of the amino acids spectrum in urine is of great interest so far as amino acids are the part of the matrix proteins of the urinary stone.

Introduction. TUrolithiasis is a widespread disease. In 2019 year 889,891 cases of this disease detected in Russia, and the increase in morbidity since 2005 was 35.5%. The share of urolithiasis accounts for up to 50-60% of patients in urological hospitals, often hospitalized for emergency indications. At the same time, there are no specialized questionnaires aimed at identifying risk factors for urolithiasis.

The purpose of the work: to study the use of questionnaires for the timely detection of urinary tract stones.

Introduction. Presence of calculus in an enlarged isolated renal calyx requires endoscopic or percutaneous correction to remove the calculus and eliminate the cause of local urodynamic disorders. If the calyx is significantly enlarged or the parenchyma over the enlarged calyx is atrophied, the possibilities of endoscopic or percutaneous surgery may not be enough. In such a situation, laparoscopic resection of the kidney segment can be an effective method of correction.

Introduction. Abdominal obesity has been considered an important risk factor for the development of urolithiasis in recent years. In this paper, we investigated the influence of the degree of obesity in patients with urolithiasis on metabolic parameters and the frequency of detection of urinary stones of various chemical compositions.

Introduction. Various forms of urolithiasis are associated with a number of disorders and diseases in the pathogenesis of which lipid metabolism plays a significant role.

Objective. To determine the stereotype of consumption of fats, saturated fatty acids and cholesterol by patients with calcium and non-calcium urolithiasis.

Introduction. Purine dysmetabolism is occured by increased production of uric acid, which leads to hyperuricemia and hyperuricuria. The most common forms of purine metabolism disorders are the uratenephropathy, gout, and asymptomatic hyperuricemia.

Purpose. To evaluate the data published from 1992 to 2021 on the prevalence, forms of purine metabolism disorders, diagnostics and methods of their treatment. Two hundred and seventy original publications were identified, of which 37 were selected and analyzed.

ВВЕДЕНИЕ

Коррекция нарушений мочеиспускания, которые могут наблюдаться у 10-90% неврологических больных, несмотря на достижения современной медицины, остается неразрешенной проблемой [1].

Relevance. Urolithiasis is still one of the most widespread and actively progressing diseases. The high incidence of complications from taking chemical drugs has become the main reason for the change in attitudes towards herbal medicines, and now the treatment with herbal medicines is returning again, revealing its benefits based on evidencebased medicine. Phytochemicals have a positive effect on the gut microbiome and are widely used to prevent and treat obesity, liver, intestinal and inflammatory diseases.

Introduction. Urolithiasis is a widespread disease with high the frequency of recurrence. An important preventive measure is an increase in daily urine output. Patients with urolithiasis need to take into account the mineral the composition of the fluid consumed, since it can affect the formation of stones. It is especially important to pay attention to the composition of bottled water purchased in retail chains due to its significant differences.

Introduction. Lithokinetic therapy after remote shock wave uretero lithotripsy (SWL) is an obligatory stage in the postoperative management of patients with urolithiasis. In the postoperative period, it is extremely important to correctly determine the required drug, its dosage and frequency of administration. According to clinical guidelines, it is customary to use standard schemes of lithokinetic therapy, including non-steroidal anti-inflammatory drugs (NSAIDs) in combination with α-blockers.