Number №4, 2019 - page 92-99

Comparative evaluation of azotemia after various options for drainage of the upper urinary tract DOI: 10.29188/2222-8543-2019-11-4-92-99

For citation: Fedorov A.A., Zolotukhin O.V., Madykin Yu.Yu., Petryaev A.V., Titova S.N., Zolotukhin V.O. Comparative evaluation of azotemia after various options for drainage of the upper urinary tract. Experimental and clinical urology 2019; (4):92-99
Fedorov A.A., Zolotuhin O.V., Madykin Yu.Yu., Petryaev A.V, , Titova S.N., Zolotuhin V.O.
Information about authors:
  • Fedorov A.A. – Urologist of Tula Regional Clinical Hospital, Tula, Russia, fdrvart@rambler.ru, ORCID 0000-0002-6298-029X
  • Zolotukhin O.V. – Doctor of Medical Sciences, Chief Urologist, Department of Health of the Voronezh Region, Deputy Chief Physician for Medical Unit of the Healthcare Institution of Higher Education, Voronezh Regional Clinical Hospital No. 1, Head of the Department of Urology and Andrology, IDPO, Associate Professor of the Department of Oncology and Specialized Surgical Disciplines, N.N. Burdenko Voronezh State Medical University of the Ministry of Health of the Russian Federation, Voronezh, Russian, zolotuhin-o@yandex.ru
  • Madykin Yu.Yu. – candidate of medical sciences, associate professor of the Department of Oncology and Specialized Surgical Disciplines N.N. Burdenko Voronezh State Medical University of the Ministry of Health of the Russian Federation, Voronezh, Russian, madykin@mail.ru
  • Petryaev A.V. – Chief Urologist, Ministry of Health of the Tula Region, Head of the Urology Department of the State Health Institution, Tula Regional Clinical Hospital, Tula, Russia, petryaev@bk.ru, ORCID 0000-0002-3108-1312
  • Titova S.N. – Assistant, Department of Public Health, Healthcare, Hygiene and Epidemiology N.N. Bur- denko Voronezh State Medical University of the Ministry of Health of the Russian Federation, Voronezh, Russian, svetik-kartashova@yandex.ru
  • Zolotukhin V.O. – 4th year student of the Faculty of Medicine N.N. Burdenko Voronezh State Medical University of the Ministry of Health of the Russian Federation, Vladimir.zolotuxin@gmail.com
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Introduction. Obstruction of the upper urinary tract is a major problem in recent clinical urology because it has a significant level of morbidity in the population and serious medical and social consequences (azotemia, renal colic, infectious and inflammatory complications, pain, renal failure). Urolithiasis, oncourological and oncogynecological pathologies together constitute an big part in the structure of the general somatic morbidity, while acute and chronic obstruction of urinary tract is their most typical complication.

Purpose. To make a comparative assessment of the effect of various options for drainage of the upper urinary tract (JJ-stenting of the ureter, ureteral catheter, percutaneous nephrostomy) during their obstruction on the history of azotemia.

Materials and methods. Three hundred patients with urological diseases corresponding to the patient’s model were assessed: «Diagnosis: urolithiasis / oncourological pathology / gynecological oncology, co-incident with obstruction of the upper urinary tract, age 30-80 years.»

Results and discussion. After resolving obstruction of the upper urinary tract, the dynamics of azotemia in terms of both urea and creatinine can have statistically significant differences depending on the method of drainage used. In terms of normalization and the number of patients with completely resolved azotemia, the method of percutaneous puncture nephrostomy comes first, ureter catheterization is in last position, in- ternal ureter stenting is an «intermediate position».

Conclusions. The obtained results should be taken into account to deepen the fundamental pathogenetic ideas about the development of azotemia under the impact of obstruction of the upper urinary tract and its resolution under the influence of various drainage methods, as well as when choosing these methods in a specific clinical situation in subsequent comprehensive studies.

Conflict of interest. The authors declare no conflict of interest.

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upper urinary tract, obstruction, drainage, ureteral stenting, ureter catheterization, percutaneous puncture nephrostomy, azotemia, urea, creatinine

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