Number №3, 2019 - page 4-10

Epidemiology of urolithiasis in Perm region: results of a 30 year study DOI: 10.29188/2222-8543-2019-11-3-4-10

Davidov M.I., Dremin E.I., Nikonova O.E., Guschina T.S.
Information about authors:
  • Davidov M.I. – PhD, assistant professor of Department of Faculty Surgery of Perm State Medical University named after Acad. E.A. Wagner of Ministry of Health of Russia, midavidov@mail.ru ORCID 0000-0002-8932-2844
  • Dremin D.I. – PhD, assistant professor of Department of Faculty Surgery of Perm State Medical University named after Acad. E.A. Wagner of Ministry of Health of Russia, head of the urology Department of PKKH, dreminperm@gmail.com
  • Nikonova O.E. – PhD, аssistant of Department of Faculty Surgery of Perm State Medical University named after Acad. E.A. Wagner of Ministry of Health of Russia, nikonova-olga@yandex.ru, ORCID 0000-0002-4829-1877
  • Gushchina T.S. – assistant of Department of faculty Surgery of Perm State Medical University named after Acad. E.A. Wagner of Ministry of Health of Russia, nikonova-olga@yandex.ru
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Contacts: Nikonova Olga Evgenievna, nikonova-olga@yandex.ru

Introduction. A typical endemic region of Russia is the Perm Territory with a population of 3.3 million people, occupying a territory equal to Denmark, the Netherlands and Belgium, and one of the ten most industrialized regions of the Russian Federation. The main source of drinking water in the region is the Kama – the 4th river of Europe.

The purpose of the study is to study the prevalence of urolithiasis, the age composition of patients, the distribution by gender, the composition of stones in an endemic region and to determine the relationship of the disease to the geochemical characteristics of drinking water.

Materials and methods. Studied the etiopathogenetic factors of urolithiasis for 30 years in 44909 people. This number includes urolithiasis patients who were treated in hospitals and clinics of the Perm region. 18619 people underwent routine examinations by urologists. population (workers Chusovskogo metallurgical plant, slave. Village Pashia, rural residents of 6 areas, students of Perm). Analyzed 2 thousand samples of drinking water of the Kama River and its tributaries by atomic absorption flame spectrophotometry. The results of the samples are compared with the prevalence of urolithiasis in the areas of the Perm Territory.

Results. The high prevalence of urolithiasis in the Perm region was revealed: according to official reports, 797 per 100,000 of the population, and during preventive examinations even higher among 10-15.6% of the population. Urolithiasis is the most common urological disease, accounting for 35.5% of all inpatient urological patients, 20.5% of visits to a polyclinic urologist, 60% in the structure of emergency urological care. Among the patients prevailed persons of working age (70.1%), men (52.4%). Calcium-oxalate type of stone formation was more common (42.2%). It has been established that the main exogenous factors of stone formation are high hardness of drinking water, increased mineralization, significant calcium content and pollution of water of organic and inorganic nature.

Conclusion. The unsatisfactory quality of drinking water of natural and man-made character is the main cause of the high prevalence of urolithiasis in the region.

For citation: Davidov M.I., Dremin D.I., Nikonova O.E., Gushchina T.S. Epidemiology of urolithiasis in Perm region: results of a 30 year study. Experimental and clinical urology 2019;(3):4-10

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urolithiasis, epidemiology of urolithiasis, prevalence, risk factors, prevention, chemical composition of stones

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