Number №4, 2019 - page 74-79

Own experience in the use of multispiral dynamic computer pharmacocavernosography in the diagnosis of venogenic erectile dysfunction DOI: 10.29188/2222-8543-2019-11-4-74-79

For citation: Popov S.V., Orlov I.N., Garapach I.A., Grin E.A., Malevich S.M., Gulko A.M., Topuzov T.M., Kyzlasov P.S. Own experience in the use of multispiral dynamic computer pharmacocavernosography in the diagnosis of venogenic erectile dysfunction. Experimental and clinical urology 2019; (4):74-79
Popov S.V., Orlov I.N., Garapach I.N., Grin' E.A., Malevich S.M., Gul'ko A.M., Topuzov T.M., Kyzlasov P.S.
Information about authors:
  • Popov S.V. – , Dr. Sc. , Professor of the Department Military-Medical Academy S.M. Kirov, chief physician of Clinical Hospital of St. Luke, E-mail: doc.popov@gmail.com, ORCID https://orcid.org/0000-0003-2767-7153
  • Orlov I. N. – PhD, Head of the Urology Department №1 City Centre Endoscopic Urology and New Technologies Clinical Hospital of St. Luke, , e-mail: doc.orlov@gmail.com, ORCID 0000-0001-5566-9789
  • Garapach I.A. – PhD, Head of the X-ray Department of Clinical Hospital of St. Luke, аssociate рrofessor of the Department of Radiology and Radiation Medicine of the First St. Petersburg State Medical University I.P. Pavlov Ministry of Health, garapach-irina@mail.ru, ORCID 0000-0001-7175-3833
  • Grin E.A. – urologist-andrologist Department of Urology №1 City Centre Endoscopic Urology and New Technologies Clinical Hospital of St. Luke, sv.lukaendouro@gmail.com, ORCID 0000-0002-8685-6525
  • Malevich S.M. – urologist Department of Urology №1 City Centre Endoscopic Urology and New Technologies Clinical Hospital of St. Luke, malevichsm@gmail.com, ORCID 0000-0002-9175-2261
  • Gulko A.M. – urologist-andrologist Department of Urology №1 City Centre Endoscopic Urology and New Technologies Clinical Hospital of St. Luke, agoolko@mail.ru, ORCID 0000-0003-4847-9519
  • Topuzov T. M. – PhD, urologist Department of Urology №1 City Centre Endoscopic Urology and New Technologies Clinical Hospital of St. Luke, ttopuzov@gmail.com, ORCID 0000-0002-5040-5546
  • Kyzlasov P.S. – Dr. Sc., Head of the Center of Urology and Andrology FMBC them. A. I. Burnazyan FMBA of Russia, dr.kyzlasov@mail.com, ORCID 0000-0003-1050-6198
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Objective. Evaluation of the Effectiveness of Dynamic Computer Pharmacocavernosography (DCCF) in Venogenic Erectile dysfunction (VED) and subsequent planning of treatment.

Materials and methods of research. Multispiral computed tomography was used to diagnose VED, followed by 3D modeling of tomograms. The study was carried out as part of a comprehensive diagnosis of 51 VED patients. The study was conducted on the computer tomograph "Aqulion PRIME," by Toshiba (Japan) under the Pelvis HCT Native protocol; 120 KV; 60 mA; Rot. Time 0.5 with subsequent processing of the obtained data with simulation (MPR and 3D reconstruction). Average age of patients– 30.7±6.7 years. At the initial stage the scanning was performed in native mode, then the intracavernous injection of alprostadil was performed. And after the erection was achieved, a contrast agent (yogexol 10 ml) diluted in 40 ml of normal saline. When half the volume of contrast substance was administered, the scanning resumed, after its completion was administered Remaining volume of contrast agent. After 50 seconds, a re-scan was performed and the study was completed.

Results. The following results were obtained in the processing of data from the DKFCG 51 patients: pathological venous drainage (PVD) Is rified in 48 (94%) patients (of which 20% was for distal HPH, 30% for proximal type HPH and 44% for mixed), Cavernous fibrosis in 2 (4%) and Peyronie 's disease in 1 (2%) patient.

Conclusion. DCFCG allows to detect VED patients the type of PVD and structural changes of cavernous tissue, which is the a dividing factor in the choice of a treatment method. Also it enables to determine the prediction of the effectiveness treatment of VED.

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erectile dysfunction, diagnosis of venogenic erectile dysfunction, dynamic computer pharmacocavernosography

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