Two new modifications of a combined
two-phasic model of the prostate
carcinogenesis are developed.
Experiments were carried out in 86
Wistar male rats. At the first variant
the rats were subjected to surgical
castration, single intraperitoneal
administration of the prolonged...
The experiments were made using
20 mature male rats (line “August”) with
a mass of 280-320 g. In 10 rats metabolic
changes typical for metabolic syndrome
(MS) were induced using high-calorie
diet (adding of 20% margarine to
standard diet and 20% of fructose to
the water...
Clinico-economical analysis was
performed for 4 different treatment
methods of the prostate cancer. The
operations performed were: open radical
retropubic prostatectomy in 215
patients, brachytherapy (I-125) in 213
patients, high intensity focused
ultrasound (HIFU) in 45 patients,...
The study of the levels of sex hormones in 35 patients with varicocele, underwent Marmar-Goldstein surgery, and 31 patients underwent surgery on the scrotum due to hydrocele, inguinal hernia, as well as other pathology of testicles.
The levels of hormones (testosterone, estradiol,...
Relevance. In males with sexual disorders hyperprolactinemia is determined in 0,4-11% of cases, and in some studies achieves 20%, due to which assessment of the prolactin level in blood is an important part of erectile dysfunction diagnostics. Objective. To study frequency of occurrence and...
Urolithiasis takes one of the first plac¬es in the structure of urological diseas¬es. Kidney and urinary tract stones are detected in 30-45% of patients admit¬ted to urological hospitals.
Significant aspects are direct cor¬relation between the stone chemical structure and increased excretion of any...
Hormone therapy (HT) for prostate cancer (PCa) is the first line drug therapy for metastatic prostate cancer. The time between the onset of hormonal medications and the development of hormone-resistance is about 12-18 months, with 15-20% of patients with tumor primary resistant to HT. As a second-...
Alpha-1 adrenergic receptors antagonists (alpha-blockers) are the most effective drugs for the treatment of patients with lower urinary tract symptoms (LUTS) caused by benign prostatic hyperplasia This article provides an overview of the pharmacological profile of a new alpha-1 adrenergic receptors...
In experiment on 20 rats we studied the effect of a 4-hour acute urinary retention (AUR) on the functional state of the bladder and the change in activity of some enzymes (AST and ALT transaminases, lactate dehydrogenase - LDH, alkaline phosphatase - ALP, y-glutamyltranspeptidase-GGTP, N-acetyl -p-...
Introduction: widespread introduction of radical prostatectomy (RPE) into clinical practice and particularly its nerve- sparing option resulted an appearance of a new type of sexual dysfunction. This type of sexual dysfunction has specific particularities of ethiology, pathogenesis, clinical...