ANDROLOGY

Nowadays, the problem of еру restoration of external male genitalia in case of their loss, inherent absence and development alterations is very actual. The main aim of surgical treatment in these situations is creation of aesthetically proper and sexually functional phallus with incorporated neo-urethra, capable for micturition. Many surgical techniques were proposed until recently.

Medications that inhibit adrenergic receptors, are used in clinical practice for a quite long time - since 1918. Discovery of different subtypes of α-adrenergic receptors and the clarification of their role allowed to create selective α1-blockers, which, compared with non-selective α-blockers have far less side effects on the cardiovascular system.

Inhibitors of phosphodiesterase type 5 are the first line in the treatment of erectile dysfunction. Recent publications indicate ambiguous influence on spermatogenesis – from stimulating up to contraceptive. In spite of high selectivity all inhibitors of type 5 phosphodiesterase effect on other PDE isoferments, located in different tissues, including PDE type 11. In experiments the influence of that particular isoferment in spermatogenesis regulation was proved.

Objective - to examine the possibility of application of flow cytometry to characterize the state of human sperm cells (viability) and the comparison of the results with the light microscopy as a conventional method in andrology. The study used vital dyes that detect damage to the cell membranes: eosin - for light microscopy and propidium iodide - for flow cytometry.

In the literary review modern data of pathophisyological role of one of the most actual modern medicine problems - Metabolic Syndrome - and associated Hormonal and Metabolic disorders at men in Prostate Diseases Pathogenesis are stated.

Currently a huge experience of using phosphodiesterase type 5 inhibitors as a standard first line therapy of erectile dysfunction was accumulated. Meanwhile high price and significant risk of undesirable effects limit their wide spread use. That’s why some patients use mediation of natural origin. One of them is Tongkat Ali Platinum, containing extract of Euricoma Longifolia Jack roots, bee’s royal jelly and Ginseng root extract.

In urological center of clinic on Gorkiy station for 4 years (from april 2008 to december 2011) we performed 211 transurethral enucleations of prostate (TUEB) in patients with BPH. Patients aged from 53 to 83 (mean 64 years). Surgery time was from 60 minutes to 190 minutes. (average 119 min.). The volume of resected tissue was from 80 to 225 ml (mean 122 ml). When performing TUEB special electrode consisting of a plunger is used for tissue enucleation. The loop electrode is used for dissection and coagulation of tissue.

The classic paradigm of obstructive benign prostate hyperplasia (BPH) causing lower urinary tract symptoms (LUTS; BPH/LUTS) has been replaced by the notion that not only the prostate but also the bladder contributes to symptoms.

Alpha-1 adrenergic receptors antagonists (alpha-blockers) are the most effective drugs for the treatment of patients with lower urinary tract symptoms (LUTS) caused by benign prostatic hyperplasia This article provides an overview of the pharmacological profile of a new alpha-1 adrenergic receptors antagonists - silodosin, especially - for the safety and portability profiles.

The study of the levels of sex hor­mones in 35 patients with varico­cele, underwent Marmar-Goldstein surgery, and 31 patients underwent surgery on the scrotum due to hydro­cele, inguinal hernia, as well as other pathology of testicles.
The levels of hormones (testosterone, estradiol, progesterone) were mea­sured in serum taken simultaneously from the cubital vein and the pampi­niform plexus vein.